4lce

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{{STRUCTURE_4lce| PDB=4lce | SCENE= }}
 
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===CtBP1 in complex with substrate MTOB===
 
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{{ABSTRACT_PUBMED_24657618}}
 
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==Function==
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==CtBP1 in complex with substrate MTOB==
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[[http://www.uniprot.org/uniprot/CTBP1_HUMAN CTBP1_HUMAN]] Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.<ref>PMID:9858600</ref> <ref>PMID:15542832</ref> <ref>PMID:19103759</ref> <ref>PMID:12419229</ref>
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<StructureSection load='4lce' size='340' side='right'caption='[[4lce]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4lce]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LCE FirstGlance]. <br>
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[[4lce]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCE OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KMT:4-(METHYLSULFANYL)-2-OXOBUTANOIC+ACID'>KMT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lce OCA], [https://pdbe.org/4lce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lce RCSB], [https://www.ebi.ac.uk/pdbsum/4lce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lce ProSAT]</span></td></tr>
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<ref group="xtra">PMID:024657618</ref><references group="xtra"/><references/>
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</table>
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[[Category: Hilbert, B J.]]
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== Function ==
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[[Category: Royer, W E.]]
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[https://www.uniprot.org/uniprot/CTBP1_HUMAN CTBP1_HUMAN] Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.<ref>PMID:9858600</ref> <ref>PMID:15542832</ref> <ref>PMID:19103759</ref> <ref>PMID:12419229</ref>
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[[Category: Schiffer, C A.]]
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== References ==
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[[Category: D-isomer 2-hydroxyacid dehydrogenase]]
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<references/>
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[[Category: Oxidoreductase-oxidoreductase substrate complex]]
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__TOC__
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[[Category: Rossman fold]]
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</StructureSection>
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[[Category: Transcriptional co-repressor]]
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Hilbert BJ]]
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[[Category: Royer Jr WE]]
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[[Category: Schiffer CA]]

Current revision

CtBP1 in complex with substrate MTOB

PDB ID 4lce

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