2mit
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of oxidized dimeric form of human defensin 5== | |
| + | <StructureSection load='2mit' size='340' side='right'caption='[[2mit]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2mit]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MIT FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mit OCA], [https://pdbe.org/2mit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mit RCSB], [https://www.ebi.ac.uk/pdbsum/2mit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mit ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DEF5_HUMAN DEF5_HUMAN] Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.<ref>PMID:12021776</ref> <ref>PMID:15616305</ref> <ref>PMID:17088326</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Defensin 3D structures|Defensin 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Nolan EM]] | ||
| + | [[Category: Wagner G]] | ||
| + | [[Category: Wommack AJ]] | ||
| + | [[Category: Ziarek JJ]] | ||
Current revision
Solution structure of oxidized dimeric form of human defensin 5
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