2qhs

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(New page: 200px<br /><applet load="2qhs" size="350" color="white" frame="true" align="right" spinBox="true" caption="2qhs, resolution 1.50&Aring;" /> '''Structural Basis of ...)
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[[Image:2qhs.jpg|left|200px]]<br /><applet load="2qhs" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2qhs, resolution 1.50&Aring;" />
 
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'''Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B'''<br />
 
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==About this Structure==
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==Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B==
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2QHS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=OCA:'>OCA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Oca+Binding+Site+For+Residue+A+3913'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHS OCA].
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<StructureSection load='2qhs' size='340' side='right'caption='[[2qhs]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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==Reference==
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<table><tr><td colspan='2'>[[2qhs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QHS FirstGlance]. <br>
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Structural basis of octanoic acid recognition by lipoate-protein ligase B., Kim DJ, Lee SJ, Kim HS, Kim KH, Lee HH, Yoon HJ, Suh SW, Proteins. 2007 Dec 12;70(4):1620-1625. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18076036 18076036]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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[[Category: Single protein]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OCA:OCTANOIC+ACID+(CAPRYLIC+ACID)'>OCA</scene></td></tr>
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[[Category: Thermus thermophilus]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qhs OCA], [https://pdbe.org/2qhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qhs RCSB], [https://www.ebi.ac.uk/pdbsum/2qhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qhs ProSAT]</span></td></tr>
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[[Category: Kim, D J.]]
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</table>
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[[Category: Kim, H S.]]
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== Function ==
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[[Category: Kim, K H.]]
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[https://www.uniprot.org/uniprot/LIPB_THET8 LIPB_THET8] Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
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[[Category: Lee, H H.]]
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== Evolutionary Conservation ==
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[[Category: Lee, S J.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Suh, S W.]]
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Check<jmol>
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[[Category: Yoon, H J.]]
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<jmolCheckbox>
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[[Category: OCA]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/2qhs_consurf.spt"</scriptWhenChecked>
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[[Category: globular protein]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: transferase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 27 07:59:00 2008''
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qhs ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Kim DJ]]
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[[Category: Kim HS]]
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[[Category: Kim KH]]
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[[Category: Lee HH]]
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[[Category: Lee SJ]]
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[[Category: Suh SW]]
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[[Category: Yoon HJ]]

Current revision

Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B

PDB ID 2qhs

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