4ouh
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the FP domain of Human PI31 Proteasome Inhibitor== | |
| - | + | <StructureSection load='4ouh' size='340' side='right'caption='[[4ouh]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ouh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OUH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ouh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ouh OCA], [https://pdbe.org/4ouh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ouh RCSB], [https://www.ebi.ac.uk/pdbsum/4ouh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ouh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PSMF1_HUMAN PSMF1_HUMAN] Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.<ref>PMID:10764772</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Du Z]] | ||
| + | [[Category: Huang X]] | ||
| + | [[Category: Shang J]] | ||
Current revision
Crystal structure of the FP domain of Human PI31 Proteasome Inhibitor
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Categories: Homo sapiens | Large Structures | Du Z | Huang X | Shang J
