This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4f2v
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_4f2v| PDB=4f2v | SCENE= }} | ||
| - | ===Crystal Structure of de novo designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR165=== | ||
| - | {{ABSTRACT_PUBMED_24705591}} | ||
| - | == | + | ==Crystal Structure of de novo designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR165== |
| - | [[4f2v]] is a 2 chain structure with sequence from [ | + | <StructureSection load='4f2v' size='340' side='right'caption='[[4f2v]], [[Resolution|resolution]] 2.49Å' scene=''> |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4f2v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F2V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F2V FirstGlance]. <br> | |
| - | < | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.493Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CXM:N-CARBOXYMETHIONINE'>CXM</scene>, <scene name='pdbligand=LMU:DODECYL-ALPHA-D-MALTOSIDE'>LMU</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f2v OCA], [https://pdbe.org/4f2v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f2v RCSB], [https://www.ebi.ac.uk/pdbsum/4f2v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f2v ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/TYSY_ECOLI TYSY_ECOLI] Provides the sole de novo source of dTMP for DNA biosynthesis. This protein also binds to its mRNA thus repressing its own translation. |
| - | [ | + | __TOC__ |
| - | [ | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Synthetic construct]] |
| - | [[Category: | + | [[Category: Acton TB]] |
| - | [[Category: | + | [[Category: Everett JK]] |
| - | [[Category: | + | [[Category: Hunt JF]] |
| - | [[Category: | + | [[Category: Kohan E]] |
| - | [[Category: | + | [[Category: Kuzin A]] |
| - | [[Category: | + | [[Category: Lew S]] |
| - | [[Category: | + | [[Category: Maglaqui M]] |
| - | [[Category: | + | [[Category: Montelione GT]] |
| - | [[Category: | + | [[Category: Rajagopalan S]] |
| - | [[Category: | + | [[Category: Seetharaman J]] |
| - | [[Category: | + | [[Category: Tong L]] |
| - | [[Category: | + | [[Category: Xiao R]] |
Current revision
Crystal Structure of de novo designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR165
| |||||||||||
Categories: Large Structures | Synthetic construct | Acton TB | Everett JK | Hunt JF | Kohan E | Kuzin A | Lew S | Maglaqui M | Montelione GT | Rajagopalan S | Seetharaman J | Tong L | Xiao R
