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Nucleosomes
From Proteopedia
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| - | + | For a general introduction beyond what is provided below, please see Wikipedia: [http://en.wikipedia.org/wiki/Nucleosomes Nucleosome]. For a list of nucleosome structures, see [[:Category:Nucleosome | Category: Nucleosome]]. | |
| - | ==Scenes for Projection in | + | ==Scenes for Projection in Biochemistry Classes== |
| - | <applet load="1aoi" size=" | + | |
| - | caption="1aoi, resolution 2.80Å" /> | + | This section offers some large scenes of a nucleosome ([[1aoi]]), as determined in [http://www.mol.biol.ethz.ch/groups/richmond Tim Richmond's lab], suitable for projection in biochemistry classes. |
| + | |||
| + | <applet load="1aoi" size="450" color="white" frame="true" align="right" caption="[[1aoi]], resolution 2.80Å" script="Nucleosomes/Rockets/1" /> | ||
<big> | <big> | ||
| - | 1. '''<scene name=' | + | 1. '''<scene name='Nucleosomes/Composition/2'>Composition</scene>: <font color='#808080'>DNA</font>, <font color='#7e6c54'>Protein</font>.''' |
| - | + | 2. '''<scene name='Nucleosomes/Dna/3'>DNA</scene>''' | |
| + | <jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>display displayed,*:i,*:j</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>hide hidden,*:i,*:j</scriptWhenUnchecked> | ||
| + | <checked>true</checked> | ||
| + | <text></text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol> | ||
| - | + | 3. '''<scene name='Nucleosomes/Histones/6'>Histones</scene>''' | |
| + | <br> | ||
| + | | ||
| + | <jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>display displayed,*:c,*:g</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>hide hidden,*:c,*:g</scriptWhenUnchecked> | ||
| + | <checked>true</checked> | ||
| + | <text></text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol><big>'''<font color='red'>H2a</font>'''</big> | ||
| + | | ||
| + | <jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>display displayed,*:d,*:h</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>hide hidden,*:d,*:h</scriptWhenUnchecked> | ||
| + | <checked>true</checked> | ||
| + | <text></text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol><big>'''<font color='orange'>H2b</font>'''</big> | ||
| + | | ||
| + | <jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>display displayed,*:a,*:e</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>hide hidden,*:a,*:e</scriptWhenUnchecked> | ||
| + | <checked>true</checked> | ||
| + | <text></text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol><big>'''<font color='green'>H3</font>'''</big> | ||
| + | | ||
| + | <jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>display displayed,*:b,*:f</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>hide hidden,*:b,*:f</scriptWhenUnchecked> | ||
| + | <checked>true</checked> | ||
| + | <text></text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol><big>'''<font color='blue'>H4</font>'''</big> | ||
| + | |||
| + | |||
| + | 4. '''<scene name='Nucleosomes/Rockets/4'>Secondary Structure</scene>''' | ||
| + | |||
| + | <ul> | ||
| + | <li><scene name='Nucleosomes/Rockets/10'>H2a and H2b only</scene></li> | ||
| + | <li><scene name='Nucleosomes/Rockets/11'>H3 and H4 only</scene></li> | ||
| + | </ul> | ||
| - | 3. '''<scene name='1aoi/Rockets/1'>Secondary Structure</scene>''' | ||
</big> | </big> | ||
| + | <scene name='1aoi/Introduction/2'>The nucleosome core particle</scene> contains two copies of each histone <font color=tan>'''protein'''</font> (<font color=tan>'''H2A, H2B, H3, H4'''</font>) and 146 basepairs (bp) of superhelical <font color=purple>'''DNA'''</font> wrapped around this histone octamer. It represents the first order of DNA packaging in the nucleus and as such is the principal structure that determines DNA accessibility (this scene was created by David Marcey, Eran Hodis, Jaime Prilusky).<br /> | ||
| + | Examples of [[Archaeal_Histones]] | ||
| + | <br clear='right'> | ||
| + | ==3D structures of histone== | ||
| - | + | [[Histone]] | |
| - | + | ||
| - | + | ==Additional Resources== | |
| - | + | For Additional Information, See: [[Nucleic Acids]] | |
| - | + | ||
| - | + | == Files for 3D printer == | |
| - | + | <i class="fas fa-cubes"></i> Nucleosome by [[User:Marius Mihasan|Marius Mihasan]] [https://3dprint.nih.gov/discover/3DPX-015090 <i class="fas fa-download"></i>] | |
| + | |||
| + | [[Category:Nucleosome]] | ||
| + | [[Category:3D printer files]] | ||
Current revision
For a general introduction beyond what is provided below, please see Wikipedia: Nucleosome. For a list of nucleosome structures, see Category: Nucleosome.
Contents |
Scenes for Projection in Biochemistry Classes
This section offers some large scenes of a nucleosome (1aoi), as determined in Tim Richmond's lab, suitable for projection in biochemistry classes.
|
1. : DNA, Protein.
2.
3.
H2a
H2b
H3
H4
4.
contains two copies of each histone protein (H2A, H2B, H3, H4) and 146 basepairs (bp) of superhelical DNA wrapped around this histone octamer. It represents the first order of DNA packaging in the nucleus and as such is the principal structure that determines DNA accessibility (this scene was created by David Marcey, Eran Hodis, Jaime Prilusky).
Examples of Archaeal_Histones
3D structures of histone
Additional Resources
For Additional Information, See: Nucleic Acids
Files for 3D printer
Nucleosome by Marius Mihasan
Proteopedia Page Contributors and Editors (what is this?)
Eran Hodis, Eric Martz, Harry Greenblatt, Jaime Prilusky, Michal Harel, Joel L. Sussman, Angel Herraez, Alexander Berchansky, Karl Oberholser, David Canner
