4q33
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4q33 is ON HOLD Authors: Maltseva, N., Kim, Y., Makowska-Grzyska, M., Mulligan, R., Gu, M., Anderson, W.F., Joachimiak, A., CSGID, Center for Struct...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and A110== | |
| + | <StructureSection load='4q33' size='340' side='right'caption='[[4q33]], [[Resolution|resolution]] 2.88Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4q33]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens_ATCC_13124 Clostridium perfringens ATCC 13124]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q33 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q33 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.885Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2YA:4-[(1R)-1-[1-(4-CHLOROPHENYL)-1,2,3-TRIAZOL-4-YL]ETHOXY]-1-OXIDANYL-QUINOLINE'>2YA</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q33 OCA], [https://pdbe.org/4q33 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q33 RCSB], [https://www.ebi.ac.uk/pdbsum/4q33 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q33 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0H2YRZ7_CLOP1 A0A0H2YRZ7_CLOP1] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] | ||
| - | + | ==See Also== | |
| - | + | *[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Clostridium perfringens ATCC 13124]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Anderson WF]] | ||
| + | [[Category: Gollapalli DR]] | ||
| + | [[Category: Gorla SK]] | ||
| + | [[Category: Gu M]] | ||
| + | [[Category: Hedstrom L]] | ||
| + | [[Category: Joachimiak A]] | ||
| + | [[Category: Kim Y]] | ||
| + | [[Category: Makowska-Grzyska M]] | ||
| + | [[Category: Maltseva N]] | ||
| + | [[Category: Mandapati K]] | ||
| + | [[Category: Mulligan R]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and A110
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