4n0i

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{{STRUCTURE_4n0i| PDB=4n0i | SCENE= }}
 
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===Crystal structure of S. cerevisiae mitochondrial GatFAB in complex with glutamine===
 
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{{ABSTRACT_PUBMED_24692665}}
 
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==Function==
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==Crystal structure of S. cerevisiae mitochondrial GatFAB in complex with glutamine==
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[[http://www.uniprot.org/uniprot/GATA_YEAST GATA_YEAST]] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for HMG2-induced ER-remodeling.<ref>PMID:19417106</ref> <ref>PMID:18667535</ref> [[http://www.uniprot.org/uniprot/GATF_YEAST GATF_YEAST]] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.<ref>PMID:19417106</ref> <ref>PMID:21799017</ref> [[http://www.uniprot.org/uniprot/GATB_YEAST GATB_YEAST]] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).<ref>PMID:19417106</ref>
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<StructureSection load='4n0i' size='340' side='right'caption='[[4n0i]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4n0i]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N0I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.001&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n0i OCA], [https://pdbe.org/4n0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n0i RCSB], [https://www.ebi.ac.uk/pdbsum/4n0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n0i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GATA_YEAST GATA_YEAST] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for HMG2-induced ER-remodeling.<ref>PMID:19417106</ref> <ref>PMID:18667535</ref>
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==About this Structure==
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==See Also==
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[[4n0i]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N0I OCA].
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*[[Glutamyl-tRNA(Gln) amidotransferase|Glutamyl-tRNA(Gln) amidotransferase]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:024692665</ref><references group="xtra"/><references/>
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__TOC__
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[[Category: Araiso, Y.]]
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</StructureSection>
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[[Category: Ishitani, R.]]
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[[Category: Large Structures]]
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[[Category: Nureki, O.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Amidotransferase]]
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[[Category: Araiso Y]]
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[[Category: Ligase]]
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[[Category: Ishitani R]]
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[[Category: Nureki O]]

Current revision

Crystal structure of S. cerevisiae mitochondrial GatFAB in complex with glutamine

PDB ID 4n0i

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