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4otm

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{{STRUCTURE_4otm| PDB=4otm | SCENE= }}
 
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===Crystal structure of the C-terminal domain from yeast GCN2===
 
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==Function==
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==Crystal structure of the C-terminal domain from yeast GCN2==
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[[http://www.uniprot.org/uniprot/GCN2_YEAST GCN2_YEAST]] Stimulates GCN4 translation in amino acid-starved cells by phosphorylating the alpha subunit of eIF-2 (SUI2) on 'Ser-52'.
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<StructureSection load='4otm' size='340' side='right'caption='[[4otm]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4otm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OTM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4otm OCA], [https://pdbe.org/4otm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4otm RCSB], [https://www.ebi.ac.uk/pdbsum/4otm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4otm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GCN2_YEAST GCN2_YEAST] Stimulates GCN4 translation in amino acid-starved cells by phosphorylating the alpha subunit of eIF-2 (SUI2) on 'Ser-52'.
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==About this Structure==
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==See Also==
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[[4otm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTM OCA].
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*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
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[[Category: Non-specific serine/threonine protein kinase]]
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__TOC__
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[[Category: Georgiadis, M M.]]
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</StructureSection>
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[[Category: He, H.]]
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[[Category: Large Structures]]
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[[Category: 4-stranded beta sheet 3 helix bundle]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: C-terminal regulatory domain]]
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[[Category: Georgiadis MM]]
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[[Category: Gcn2]]
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[[Category: He H]]
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[[Category: Regulatory domain of eif2 stress kinase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the C-terminal domain from yeast GCN2

PDB ID 4otm

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