4pwy

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{{STRUCTURE_4pwy| PDB=4pwy | SCENE= }}
 
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===Crystal structure of a Calmodulin-lysine N-methyltransferase fragment===
 
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==Disease==
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==Crystal structure of a Calmodulin-lysine N-methyltransferase fragment==
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[[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome.
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<StructureSection load='4pwy' size='340' side='right'caption='[[4pwy]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4pwy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PWY FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Catalyzes the trimethylation of 'Lys-116' in calmodulin.<ref>PMID:20975703</ref>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pwy OCA], [https://pdbe.org/4pwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pwy RCSB], [https://www.ebi.ac.uk/pdbsum/4pwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pwy ProSAT]</span></td></tr>
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[[4pwy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PWY OCA].
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</table>
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== Disease ==
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==Reference==
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[https://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome.
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<references group="xtra"/><references/>
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== Function ==
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[[Category: Calmodulin-lysine N-methyltransferase]]
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[https://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN] Catalyzes the trimethylation of 'Lys-116' in calmodulin.<ref>PMID:20975703</ref>
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[[Category: Arrowsmith, C H.]]
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== References ==
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[[Category: Bountra, C.]]
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<references/>
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[[Category: Brown, P J.]]
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__TOC__
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[[Category: Edwards, A M.]]
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</StructureSection>
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[[Category: Hong, B S.]]
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[[Category: Homo sapiens]]
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[[Category: Li, Y.]]
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[[Category: Large Structures]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Arrowsmith CH]]
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[[Category: Tempel, W.]]
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[[Category: Bountra C]]
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[[Category: Walker, J R.]]
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[[Category: Brown PJ]]
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[[Category: Methyl transferase]]
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[[Category: Edwards AM]]
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[[Category: Sgc]]
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[[Category: Hong BS]]
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[[Category: Structural genomic]]
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[[Category: Li Y]]
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[[Category: Structural genomics consortium]]
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[[Category: Tempel W]]
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[[Category: Transferase]]
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[[Category: Walker JR]]

Current revision

Crystal structure of a Calmodulin-lysine N-methyltransferase fragment

PDB ID 4pwy

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