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1ljr

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{{STRUCTURE_1ljr| PDB=1ljr | SCENE= }}
 
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===GLUTATHIONE TRANSFERASE (HGST T2-2) FROM HUMAN===
 
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{{ABSTRACT_PUBMED_9551553}}
 
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==Function==
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==GLUTATHIONE TRANSFERASE (HGST T2-2) FROM HUMAN==
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[[http://www.uniprot.org/uniprot/GSTT2_HUMAN GSTT2_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.
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<StructureSection load='1ljr' size='340' side='right'caption='[[1ljr]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1ljr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LJR FirstGlance]. <br>
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[[1ljr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LJR OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ljr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ljr OCA], [https://pdbe.org/1ljr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ljr RCSB], [https://www.ebi.ac.uk/pdbsum/1ljr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ljr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GSTT2_HUMAN GSTT2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lj/1ljr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ljr ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Glutathione S-transferase|Glutathione S-transferase]]
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:009551553</ref><references group="xtra"/><references/>
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[[Category: Glutathione transferase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Board, P G.]]
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[[Category: Large Structures]]
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[[Category: Chelvanayagam, G.]]
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[[Category: Board PG]]
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[[Category: Flanagan, J.]]
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[[Category: Chelvanayagam G]]
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[[Category: Mckinstry, W J.]]
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[[Category: Flanagan J]]
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[[Category: Oakley, A J.]]
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[[Category: Mckinstry WJ]]
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[[Category: Parker, M W.]]
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[[Category: Oakley AJ]]
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[[Category: Rossjohn, J.]]
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[[Category: Parker MW]]
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[[Category: Tan, K L.]]
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[[Category: Rossjohn J]]
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[[Category: Verger, D.]]
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[[Category: Tan KL]]
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[[Category: Transferase]]
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[[Category: Verger D]]

Current revision

GLUTATHIONE TRANSFERASE (HGST T2-2) FROM HUMAN

PDB ID 1ljr

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