This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1ms1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:40, 10 April 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_1ms1| PDB=1ms1 | SCENE= }}
 
-
===Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)===
 
-
{{ABSTRACT_PUBMED_12419220}}
 
-
==About this Structure==
+
==Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)==
-
[[1ms1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MS1 OCA].
+
<StructureSection load='1ms1' size='340' side='right'caption='[[1ms1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1ms1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MS1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MS1 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ms1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ms1 OCA], [https://pdbe.org/1ms1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ms1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ms1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ms1 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q26966_TRYCR Q26966_TRYCR]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1ms1_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ms1 ConSurf].
 +
<div style="clear:both"></div>
-
==Reference==
+
==See Also==
-
<ref group="xtra">PMID:012419220</ref><references group="xtra"/><references/>
+
*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
-
[[Category: Exo-alpha-sialidase]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
-
[[Category: Alzari, P M.]]
+
[[Category: Alzari PM]]
-
[[Category: Amaya, M F.]]
+
[[Category: Amaya MF]]
-
[[Category: Buschiazzo, A.]]
+
[[Category: Buschiazzo A]]
-
[[Category: Cremona, M L.]]
+
[[Category: Cremona ML]]
-
[[Category: Frasch, A C.]]
+
[[Category: Frasch AC]]
-
[[Category: Beta-propeller]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Protein-carbohydrate interaction]]
+
-
[[Category: Sialidase]]
+
-
[[Category: Transglycosylation]]
+

Current revision

Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)

PDB ID 1ms1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools