1gr0

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{{STRUCTURE_1gr0| PDB=1gr0 | SCENE= }}
 
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===MYO-INOSITOL 1-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NAD AND ZINC.===
 
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{{ABSTRACT_PUBMED_12005437}}
 
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==Function==
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==myo-inositol 1-phosphate synthase from Mycobacterium tuberculosis in complex with NAD and zinc.==
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[[http://www.uniprot.org/uniprot/Y046_MYCTU Y046_MYCTU]] Catalyzes the conversion of glucose 6-phosphate to 1D-myo-inositol 3-phosphate (By similarity).
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<StructureSection load='1gr0' size='340' side='right'caption='[[1gr0]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1gr0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GR0 FirstGlance]. <br>
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[[1gr0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR0 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr0 OCA], [https://pdbe.org/1gr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gr0 RCSB], [https://www.ebi.ac.uk/pdbsum/1gr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gr0 ProSAT], [https://www.topsan.org/Proteins/TBSGC/1gr0 TOPSAN]</span></td></tr>
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<ref group="xtra">PMID:012005437</ref><references group="xtra"/><references/>
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</table>
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[[Category: Inositol-3-phosphate synthase]]
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== Function ==
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[https://www.uniprot.org/uniprot/INO1_MYCTU INO1_MYCTU] Catalyzes the conversion of glucose 6-phosphate to 1D-myo-inositol 3-phosphate.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gr/1gr0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gr0 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Mcdonald, N Q.]]
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[[Category: McDonald NQ]]
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[[Category: Murray-Rust, J.]]
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[[Category: Murray-Rust J]]
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[[Category: Norman, R A.]]
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[[Category: Norman RA]]
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[[Category: Tb , Tb Structural Genomics Consortium]]
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[[Category: Isomerase]]
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[[Category: Oxidoreductase]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Tb]]
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[[Category: Tb structural genomics consortium]]
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[[Category: Tbsgc]]
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Current revision

myo-inositol 1-phosphate synthase from Mycobacterium tuberculosis in complex with NAD and zinc.

PDB ID 1gr0

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