1q44

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{{STRUCTURE_1q44| PDB=1q44 | SCENE= }}
 
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===Crystal Structure of an Arabidopsis Thaliana Putative Steroid Sulfotransferase===
 
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==Function==
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==Crystal Structure of an Arabidopsis Thaliana Putative Steroid Sulfotransferase==
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[[http://www.uniprot.org/uniprot/FSTL_ARATH FSTL_ARATH]] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the stereospecific sulfate conjugation of 24-epibrassinosteroids. Preferred substrates are 24-epicathasterone and 6-deoxo-24-epicathasterone. Low activity with 22-deoxy-24-epiteasterone. No activity with 24-epimers catasterone and brassinolide. Sulfonates salicylic acid. May be involved in detoxification. Enhances plant response to pathogen infection and contributes to long distance signaling in systemic acquired resistance (SAR).<ref>PMID:17039368</ref> <ref>PMID:20374532</ref>
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<StructureSection load='1q44' size='340' side='right'caption='[[1q44]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1q44]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q44 FirstGlance]. <br>
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[[1q44]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q44 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q44 OCA], [https://pdbe.org/1q44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q44 RCSB], [https://www.ebi.ac.uk/pdbsum/1q44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q44 ProSAT], [https://www.topsan.org/Proteins/CESG/1q44 TOPSAN]</span></td></tr>
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<ref group="xtra">PMID:015317023</ref><references group="xtra"/><references/>
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</table>
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[[Category: Arabidopsis thaliana]]
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== Function ==
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[[Category: Bingman, C A.]]
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[https://www.uniprot.org/uniprot/SOT12_ARATH SOT12_ARATH] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the stereospecific sulfate conjugation of 24-epibrassinosteroids. Preferred substrates are 24-epicathasterone and 6-deoxo-24-epicathasterone. Low activity with 22-deoxy-24-epiteasterone. No activity with 24-epimers catasterone and brassinolide. Sulfonates salicylic acid. May be involved in detoxification. Enhances plant response to pathogen infection and contributes to long distance signaling in systemic acquired resistance (SAR).<ref>PMID:17039368</ref> <ref>PMID:20374532</ref>
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[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
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== Evolutionary Conservation ==
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[[Category: Johnson, K A.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Phillips, G N.]]
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Check<jmol>
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[[Category: Smith, D W.]]
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<jmolCheckbox>
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[[Category: Apo]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q4/1q44_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q44 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Center for eukaryotic structural genomic]]
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[[Category: Large Structures]]
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[[Category: Cesg]]
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[[Category: Bingman CA]]
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[[Category: Protein structure initiative]]
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[[Category: Johnson KA]]
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[[Category: Steroid sulfotransferase]]
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[[Category: Phillips Jr GN]]
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[[Category: Structural genomic]]
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[[Category: Smith DW]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of an Arabidopsis Thaliana Putative Steroid Sulfotransferase

PDB ID 1q44

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