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1mbe
From Proteopedia
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| - | {{STRUCTURE_1mbe| PDB=1mbe | SCENE= }} | ||
| - | ===MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 1=== | ||
| - | {{ABSTRACT_PUBMED_7796266}} | ||
| - | == | + | ==MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 1== |
| - | [[http://www.uniprot.org/uniprot/MYB_MOUSE MYB_MOUSE | + | <StructureSection load='1mbe' size='340' side='right'caption='[[1mbe]]' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1mbe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MBE FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mbe OCA], [https://pdbe.org/1mbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mbe RCSB], [https://www.ebi.ac.uk/pdbsum/1mbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mbe ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MYB_MOUSE MYB_MOUSE] Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mb/1mbe_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mbe ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Transcriptional activator|Transcriptional activator]] | + | *[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Large Structures]] |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Aimoto | + | [[Category: Aimoto S]] |
| - | [[Category: Ametani | + | [[Category: Ametani Y]] |
| - | [[Category: Hirata | + | [[Category: Hirata Z]] |
| - | [[Category: Hojo | + | [[Category: Hojo H]] |
| - | [[Category: Ishii | + | [[Category: Ishii S]] |
| - | [[Category: Morikawa | + | [[Category: Morikawa S]] |
| - | [[Category: Nakamura | + | [[Category: Nakamura H]] |
| - | [[Category: Nishimura | + | [[Category: Nishimura Y]] |
| - | [[Category: Ogata | + | [[Category: Ogata K]] |
| - | [[Category: Sarai | + | [[Category: Sarai A]] |
| - | [[Category: Yoshimura | + | [[Category: Yoshimura S]] |
| - | [[Category: Zhang | + | [[Category: Zhang R]] |
| - | + | ||
| - | + | ||
Current revision
MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 1
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Categories: Large Structures | Mus musculus | Aimoto S | Ametani Y | Hirata Z | Hojo H | Ishii S | Morikawa S | Nakamura H | Nishimura Y | Ogata K | Sarai A | Yoshimura S | Zhang R
