1lv2
From Proteopedia
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| - | {{STRUCTURE_1lv2| PDB=1lv2 | SCENE= }} | ||
| - | ===Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids=== | ||
| - | {{ABSTRACT_PUBMED_12220494}} | ||
| - | == | + | ==Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids== |
| - | [[ | + | <StructureSection load='1lv2' size='340' side='right'caption='[[1lv2]], [[Resolution|resolution]] 2.70Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1lv2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV2 FirstGlance]. <br> |
| - | [[1lv2]] is a 1 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv2 OCA], [https://pdbe.org/1lv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv2 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv2 ProSAT]</span></td></tr> |
| - | < | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HNF4G_HUMAN HNF4G_HUMAN] Transcription factor. Has a lower transcription activation potential than HNF4-alpha. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lv2_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lv2 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Davis | + | [[Category: Large Structures]] |
| - | [[Category: Johnson | + | [[Category: Davis RG]] |
| - | [[Category: Miller | + | [[Category: Johnson R]] |
| - | [[Category: Moore | + | [[Category: Miller AB]] |
| - | [[Category: Sefler | + | [[Category: Moore JT]] |
| - | [[Category: Shearer | + | [[Category: Sefler A]] |
| - | [[Category: Spitzer | + | [[Category: Shearer B]] |
| - | [[Category: Williams | + | [[Category: Spitzer T]] |
| - | [[Category: Willson | + | [[Category: Williams SP]] |
| - | [[Category: Wisely | + | [[Category: Willson TM]] |
| - | + | [[Category: Wisely B]] | |
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Current revision
Hepatocyte Nuclear Factor 4 is a Transcription Factor that Constitutively Binds Fatty Acids
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Categories: Homo sapiens | Large Structures | Davis RG | Johnson R | Miller AB | Moore JT | Sefler A | Shearer B | Spitzer T | Williams SP | Willson TM | Wisely B
