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4lmg

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{{STRUCTURE_4lmg| PDB=4lmg | SCENE= }}
 
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===Crystal structure of AFT2 in complex with DNA===
 
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{{ABSTRACT_PUBMED_24591629}}
 
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==Function==
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==Crystal structure of AFT2 in complex with DNA==
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[[http://www.uniprot.org/uniprot/AFT2_YEAST AFT2_YEAST]] Transcription factor required for iron homeostasis and resistance to oxidative stress. With RCS1, activates the gene expression in response to low-iron conditions, also called iron regulon.<ref>PMID:11448968</ref> <ref>PMID:11734641</ref> <ref>PMID:12756250</ref> <ref>PMID:15649888</ref> <ref>PMID:16024809</ref>
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<StructureSection load='4lmg' size='340' side='right'caption='[[4lmg]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lmg]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LMG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LMG FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lmg OCA], [https://pdbe.org/4lmg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lmg RCSB], [https://www.ebi.ac.uk/pdbsum/4lmg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lmg ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AFT2_YEAST AFT2_YEAST] Transcription factor required for iron homeostasis and resistance to oxidative stress. With RCS1, activates the gene expression in response to low-iron conditions, also called iron regulon.<ref>PMID:11448968</ref> <ref>PMID:11734641</ref> <ref>PMID:12756250</ref> <ref>PMID:15649888</ref> <ref>PMID:16024809</ref>
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==About this Structure==
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==See Also==
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[[4lmg]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LMG OCA].
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:024591629</ref><references group="xtra"/><references/>
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__TOC__
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[[Category: Baker's yeast]]
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</StructureSection>
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[[Category: He, C.]]
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[[Category: Large Structures]]
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[[Category: Poor, C B.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Sanishvili, R.]]
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[[Category: He C]]
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[[Category: Schuermann, J P.]]
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[[Category: Poor CB]]
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[[Category: Dna binding]]
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[[Category: Sanishvili R]]
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[[Category: Iron binding]]
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[[Category: Schuermann JP]]
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[[Category: Transcription activator-dna complex]]
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[[Category: Transcription factor]]
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[[Category: Wrky-gcm1]]
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[[Category: Wrky-gcm1 fold]]
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Current revision

Crystal structure of AFT2 in complex with DNA

PDB ID 4lmg

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