4pdc
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D== | |
| + | <StructureSection load='4pdc' size='340' side='right'caption='[[4pdc]], [[Resolution|resolution]] 1.99Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Cowpox_virus Cowpox virus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PDC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.991Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pdc OCA], [https://pdbe.org/4pdc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pdc RCSB], [https://www.ebi.ac.uk/pdbsum/4pdc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pdc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | ||
| - | + | ==See Also== | |
| - | + | *[[NK cell receptor|NK cell receptor]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Cowpox virus]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fremont DH]] | ||
| + | [[Category: Lazear E]] | ||
| + | [[Category: Nelson CA]] | ||
Current revision
Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D
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