4n7u

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{{STRUCTURE_4n7u| PDB=4n7u | SCENE= }}
 
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===Crystal Structure of Intracellular B30.2 Domain of BTN3A1 in Complex with CHDMAPP===
 
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{{ABSTRACT_PUBMED_24703779}}
 
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==Function==
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==Crystal Structure of Intracellular B30.2 Domain of BTN3A1 in Complex with CHDMAPP==
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[[http://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN]] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref>
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<StructureSection load='4n7u' size='340' side='right'caption='[[4n7u]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4n7u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N7U FirstGlance]. <br>
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[[4n7u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N7U OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4598&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2JA:[(E)-4-METHYL-5-OXIDANYL-PENT-3-ENYL]-PHOSPHONOOXY-PHOSPHINIC+ACID'>2JA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n7u OCA], [https://pdbe.org/4n7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n7u RCSB], [https://www.ebi.ac.uk/pdbsum/4n7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n7u ProSAT]</span></td></tr>
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<ref group="xtra">PMID:024703779</ref><references group="xtra"/><references/>
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</table>
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[[Category: Adams, E J.]]
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== Function ==
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[[Category: Sandstrom, A.]]
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[https://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref>
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[[Category: B30 2]]
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== References ==
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[[Category: Butyrophilin]]
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<references/>
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[[Category: Cd277]]
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__TOC__
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[[Category: Phosphoantigen]]
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</StructureSection>
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[[Category: Pry/spry]]
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[[Category: Homo sapiens]]
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[[Category: Signaling protein]]
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[[Category: Large Structures]]
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[[Category: Adams EJ]]
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[[Category: Sandstrom A]]

Current revision

Crystal Structure of Intracellular B30.2 Domain of BTN3A1 in Complex with CHDMAPP

PDB ID 4n7u

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