2hfu

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{{STRUCTURE_2hfu| PDB=2hfu | SCENE= }}
 
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===Crystal structure of L. major mevalonate kinase in complex with R-mevalonate===
 
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{{ABSTRACT_PUBMED_17397541}}
 
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==About this Structure==
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==Crystal structure of L. major mevalonate kinase in complex with R-mevalonate==
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[[2hfu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leima Leima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HFU OCA].
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<StructureSection load='2hfu' size='340' side='right'caption='[[2hfu]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2hfu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HFU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MEV:(R)-MEVALONATE'>MEV</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hfu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hfu OCA], [https://pdbe.org/2hfu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hfu RCSB], [https://www.ebi.ac.uk/pdbsum/2hfu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hfu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q4Q6K7_LEIMA Q4Q6K7_LEIMA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/2hfu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hfu ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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<ref group="xtra">PMID:017397541</ref><references group="xtra"/><references/>
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*[[Mevalonate kinase|Mevalonate kinase]]
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[[Category: Leima]]
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__TOC__
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[[Category: Mevalonate kinase]]
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</StructureSection>
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[[Category: Hunter, W N.]]
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[[Category: Large Structures]]
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[[Category: Sgraja, T.]]
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[[Category: Leishmania major]]
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[[Category: Ghmp kinase]]
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[[Category: Hunter WN]]
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[[Category: Mevalonate kinase]]
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[[Category: Sgraja T]]
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[[Category: Transferase]]
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[[Category: Trypanosomatid parasite]]
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Current revision

Crystal structure of L. major mevalonate kinase in complex with R-mevalonate

PDB ID 2hfu

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