This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2a5z
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_2a5z| PDB=2a5z | SCENE= }} | ||
| - | ===Crystal Structure of Protein of Unknown Function SO2946 from Shewanella oneidensis MR-1=== | ||
| - | {{ABSTRACT_PUBMED_18566914}} | ||
| - | == | + | ==Crystal Structure of Protein of Unknown Function SO2946 from Shewanella oneidensis MR-1== |
| - | [[2a5z]] is a 3 chain structure with sequence from [ | + | <StructureSection load='2a5z' size='340' side='right'caption='[[2a5z]], [[Resolution|resolution]] 2.02Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2a5z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_oneidensis_MR-1 Shewanella oneidensis MR-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A5Z FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a5z OCA], [https://pdbe.org/2a5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a5z RCSB], [https://www.ebi.ac.uk/pdbsum/2a5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a5z ProSAT], [https://www.topsan.org/Proteins/MCSG/2a5z TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q8ED25_SHEON Q8ED25_SHEON] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of the uncharacterized protein SO2946 from Shewanella oneidensis MR-1 was determined with single-wavelength anomalous diffraction (SAD) and refined to 2.0 A resolution. The SO2946 protein consists of a short helical N-terminal domain and a large C-terminal domain with the "jelly-roll" topology. The protein assembles into a propeller consisting of three C-terminal blades arranged around a central core formed by the N-terminal domains. The function of SO2946 could not be inferred from the sequence since the protein represents an orphan with no sequence homologs, but the protein's structure bears a fold similar to that of proteins containing carbohydrate-binding modules. Features such as fold conservation, the presence of a conserved groove and a metal binding region are indicative that SO2946 may be an enzyme and could be involved in binding carbohydrate molecules. | ||
| - | + | Structure of SO2946 orphan from Shewanella oneidensis shows "jelly-roll" fold with carbohydrate-binding module.,Nocek B, Bigelow L, Abdullah J, Joachimiak A J Struct Funct Genomics. 2008 Dec;9(1-4):1-6. Epub 2008 Jun 20. PMID:18566914<ref>PMID:18566914</ref> | |
| - | <ref | + | |
| - | [[Category: | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | [[Category: Abdullah | + | </div> |
| - | [[Category: Bigelow | + | <div class="pdbe-citations 2a5z" style="background-color:#fffaf0;"></div> |
| - | [[Category: Collart | + | == References == |
| - | [[Category: Joachimiak | + | <references/> |
| - | + | __TOC__ | |
| - | [[Category: Nocek | + | </StructureSection> |
| - | + | [[Category: Large Structures]] | |
| - | + | [[Category: Shewanella oneidensis MR-1]] | |
| - | + | [[Category: Abdullah J]] | |
| - | + | [[Category: Bigelow L]] | |
| - | + | [[Category: Collart F]] | |
| - | + | [[Category: Joachimiak A]] | |
| - | + | [[Category: Nocek B]] | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Protein of Unknown Function SO2946 from Shewanella oneidensis MR-1
| |||||||||||
