This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Glycerate kinase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: This page has no information on glycerate kinases yet. Please add what you know by editing this page. More information on glycerate kinases can be found at [http://en.wikipedia.org/wiki/...)
Current revision (13:40, 3 March 2020) (edit) (undo)
 
(23 intermediate revisions not shown.)
Line 1: Line 1:
-
This page has no information on glycerate kinases yet. Please add what you know by editing this page.
+
<StructureSection load='' size='350' side='right' caption='Glycerate kinase dimer complex with sulfate ions (PDB code [[1to6]]).' scene='Glycerate_kinase/Glycerate_kinase/1'>
 +
== Function ==
 +
'''Glycerate kinase''' (GK) catalyzes the conversion of ATP + glycerate to ADP + 3-phospho-glycerate. GK participates in the metabolic pathways of serine/glycine/threonine, glycolipid and glyoxylate-dicarboxylate. GK is the last step in the pathway which starts with glucose and ends with 2-phosphoglycerate<ref>PMID:5325263</ref>.
-
More information on glycerate kinases can be found at [http://en.wikipedia.org/wiki/Glycerate_kinase Wikipedia's glycerate kinase] page.
+
== Disease ==
 +
Mutation in GK is the cause of inherited D-glyceric acidemia (D-glyceric aciduria)<ref>PMID:20949620</ref>.
 +
</StructureSection>
 +
== 3D Structures of glycerate kinase ==
 +
 
 +
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
 
 +
[[1to6]] – GK – ''Neisseria meningitides''<br />
 +
[[2b8n]] – GK – ''Thermotoga maritima''<br />
 +
[[1x3l]] – GK – ''Pyrococcus horikoshii''<br />
 +
[[3cwc]] – GK – ''Salmonella enterica''<br />
 +
[[6ckg]] – GK – ''Cryptococcus neoformans''<br />
 +
 
 +
== References ==
 +
<references/>
 +
[[Category:Topic Page]]

Current revision

Glycerate kinase dimer complex with sulfate ions (PDB code 1to6).

Drag the structure with the mouse to rotate

3D Structures of glycerate kinase

Updated on 03-March-2020

1to6 – GK – Neisseria meningitides
2b8n – GK – Thermotoga maritima
1x3l – GK – Pyrococcus horikoshii
3cwc – GK – Salmonella enterica
6ckg – GK – Cryptococcus neoformans

References

  1. ↑ Doughty CC, Hayashi JA, Guenther HL. Purification and properties of D-glycerate 3-kinase from Escherichia coli. J Biol Chem. 1966 Feb 10;241(3):568-72. PMID:5325263
  2. ↑ Sass JO, Fischer K, Wang R, Christensen E, Scholl-Burgi S, Chang R, Kapelari K, Walter M. D-glyceric aciduria is caused by genetic deficiency of D-glycerate kinase (GLYCTK). Hum Mutat. 2010 Dec;31(12):1280-5. doi: 10.1002/humu.21375. Epub 2010 Nov 9. PMID:20949620 doi:http://dx.doi.org/10.1002/humu.21375

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Eran Hodis

Retrieved from "http://52.214.119.220/wiki/index.php/Glycerate_kinase"
Personal tools