1yxo

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{{STRUCTURE_1yxo| PDB=1yxo | SCENE= }}
 
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===Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593===
 
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==Function==
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==Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593==
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[[http://www.uniprot.org/uniprot/PDXA1_PSEAE PDXA1_PSEAE]] Catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity).[HAMAP-Rule:MF_00536]
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<StructureSection load='1yxo' size='340' side='right'caption='[[1yxo]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1yxo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YXO FirstGlance]. <br>
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[[1yxo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YXO OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
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[[Category: 4-hydroxythreonine-4-phosphate dehydrogenase]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yxo OCA], [https://pdbe.org/1yxo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yxo RCSB], [https://www.ebi.ac.uk/pdbsum/1yxo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yxo ProSAT], [https://www.topsan.org/Proteins/MCSG/1yxo TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PDXA_PSEAE PDXA_PSEAE] Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).[HAMAP-Rule:MF_00536]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/1yxo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yxo ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Dong, A.]]
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[[Category: Dong A]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Kudritskam, M.]]
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[[Category: Kudritskam M]]
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[[Category: Liu, Y.]]
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[[Category: Liu Y]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Pai EF]]
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[[Category: Pai, E F.]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A.]]
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[[Category: Xu X]]
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[[Category: Xu, X.]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Oxidoreductase]]
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[[Category: Pa0593]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Pyridoxine biosynthesis]]
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[[Category: Structural genomic]]
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Current revision

Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593

PDB ID 1yxo

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