1xxb

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{{STRUCTURE_1xxb| PDB=1xxb | SCENE= }}
 
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===C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX===
 
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{{ABSTRACT_PUBMED_8594204}}
 
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==Function==
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==C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX==
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[[http://www.uniprot.org/uniprot/ARGR_ECOLI ARGR_ECOLI]] Negatively controls the expression of the four operons of arginine biosynthesis in addition to the carAB operon. Predominantly interacts with A/T residues in ARG boxes. It also binds to a specific site in cer locus. Thus it is essential for cer-mediated site-specific recombination in ColE1. It is necessary for monomerization of the plasmid ColE1.
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<StructureSection load='1xxb' size='340' side='right'caption='[[1xxb]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1xxb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XXB FirstGlance]. <br>
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[[1xxb]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXB OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xxb OCA], [https://pdbe.org/1xxb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xxb RCSB], [https://www.ebi.ac.uk/pdbsum/1xxb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xxb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARGR_ECOLI ARGR_ECOLI] Negatively controls the expression of the four operons of arginine biosynthesis in addition to the carAB operon. Predominantly interacts with A/T residues in ARG boxes. It also binds to a specific site in cer locus. Thus it is essential for cer-mediated site-specific recombination in ColE1. It is necessary for monomerization of the plasmid ColE1.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xx/1xxb_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xxb ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Arginine repressor|Arginine repressor]]
*[[Arginine repressor|Arginine repressor]]
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*[[Arginine repressor 3D structures|Arginine repressor 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:008594204</ref><references group="xtra"/><references/>
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</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Duyne, G D.Van.]]
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[[Category: Large Structures]]
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[[Category: Ghosh, G.]]
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[[Category: Ghosh G]]
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[[Category: Maas, W K.]]
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[[Category: Maas WK]]
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[[Category: Sigler, P B.]]
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[[Category: Sigler PB]]
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[[Category: Van Duyne GD]]

Current revision

C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX

PDB ID 1xxb

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