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2ehj

From Proteopedia

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(New page: 200px<br /><applet load="2ehj" size="350" color="white" frame="true" align="right" spinBox="true" caption="2ehj, resolution 2.80&Aring;" /> '''Structure of Uracil ...)
Current revision (08:40, 25 October 2023) (edit) (undo)
 
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[[Image:2ehj.jpg|left|200px]]<br /><applet load="2ehj" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2ehj, resolution 2.80&Aring;" />
 
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'''Structure of Uracil phosphoribosyl transferase'''<br />
 
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==About this Structure==
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==Structure of Uracil phosphoribosyl transferase==
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2EHJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Uracil_phosphoribosyltransferase Uracil phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.9 2.4.2.9] Known structural/functional Sites: <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+209'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+B+209'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+C+209'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+D+209'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+A+210'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+B+210'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+C+210'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+D+210'>AC8</scene>, <scene name='pdbsite=AC9:So4+Binding+Site+For+Residue+A+211'>AC9</scene>, <scene name='pdbsite=BC1:So4+Binding+Site+For+Residue+C+211'>BC1</scene>, <scene name='pdbsite=BC2:So4+Binding+Site+For+Residue+D+211'>BC2</scene>, <scene name='pdbsite=BC3:So4+Binding+Site+For+Residue+A+212'>BC3</scene>, <scene name='pdbsite=BC4:So4+Binding+Site+For+Residue+B+211'>BC4</scene>, <scene name='pdbsite=BC5:So4+Binding+Site+For+Residue+C+212'>BC5</scene>, <scene name='pdbsite=BC6:So4+Binding+Site+For+Residue+D+212'>BC6</scene>, <scene name='pdbsite=BC7:So4+Binding+Site+For+Residue+D+213'>BC7</scene>, <scene name='pdbsite=BC8:So4+Binding+Site+For+Residue+C+213'>BC8</scene>, <scene name='pdbsite=BC9:So4+Binding+Site+For+Residue+A+213'>BC9</scene> and <scene name='pdbsite=CC1:So4+Binding+Site+For+Residue+B+212'>CC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EHJ OCA].
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<StructureSection load='2ehj' size='340' side='right'caption='[[2ehj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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[[Category: Escherichia coli]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2ehj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EHJ FirstGlance]. <br>
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[[Category: Uracil phosphoribosyltransferase]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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[[Category: Lokanath, N K.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ehj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ehj OCA], [https://pdbe.org/2ehj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ehj RCSB], [https://www.ebi.ac.uk/pdbsum/2ehj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ehj ProSAT], [https://www.topsan.org/Proteins/RSGI/2ehj TOPSAN]</span></td></tr>
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[[Category: SO4]]
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</table>
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[[Category: national project on protein structural and functional analyse]]
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== Function ==
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[[Category: nppsfa]]
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[https://www.uniprot.org/uniprot/UPP_ECOLI UPP_ECOLI] Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.[HAMAP-Rule:MF_01218_B]
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[[Category: riken structural genomics/proteomics initiative]]
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== Evolutionary Conservation ==
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[[Category: rsgi]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: structural genomic]]
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Check<jmol>
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[[Category: uracil phosphoribosyl transferase]]
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/2ehj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ehj ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Mar 14 09:30:10 2008''
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==See Also==
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Lokanath NK]]

Current revision

Structure of Uracil phosphoribosyl transferase

PDB ID 2ehj

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