Ribosomal protein S6

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[[Image:RPS6.png|left|200px|thumb|Crystal Structure of Ribosomal protein S6 from [[2zm6]], chain F]]
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<StructureSection load='2bvz' size='350' side='right' scene='' caption='Ribosomal protein S6 (PDB code [[2bvz]])'>
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{{STRUCTURE_2bvz| PDB=2bvz | SIZE=400| SCENE=|right|CAPTION=Ribosomal protein S6 from [[2bvz]]}}
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[[Ribosomal protein S6]] (RPS6) is one of the 21 proteins which belong to the 30S <scene name='Ribosomal_protein_S6/Cv/2'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]] or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. It has a role in regulating translation of RNAs that contain the 5' terminal sequence<ref>PMID:16679021</ref>. It is regulated by ribosomal S6 kinase.
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</StructureSection>
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[[Ribosomal protein S6]] (RPS6) is one of the 22 proteins which belong to the <scene name='Ribosomal_protein_S6/Cv/2'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]]. It has a role in regulating translation of RNAs that contain the 5' terminal sequence. It is regulated by ribosomal S6 kinase.
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The images at the left and at the right correspond to one representative RPS6, ''i.e.'' the crystal structure of Ribosomal protein S6 from ''Thermus thermophilus'' ([[2zm6]], chain F).
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{{TOC limit|limit=2}}
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== 3D Structures of Ribosomal protein S6 ==
== 3D Structures of Ribosomal protein S6 ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===RPS6===
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*Ribosomal protein S6
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[[2kjv]] – TtRPS6 – NMR - ''Thermus thermophilus''<br />
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[[2kjw]] – TtRPS6 (mutant)– NMR<br />
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[[2bvz]], [[1ris]], [[3zzp]] – TtRPS6<br />
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[[2bxj]], [[1cqm]], [[1cqn]], [[1qjh]], [[1lou]] - TtRPS6 (mutant)<br />
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[[2j5a]] – RPS6 – ''Aquifex aeolicus''<br />
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[[1vmb]] – RPS6 – ''Thermotoga maritima''<br />
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[[3r3t]] – RPS6 – ''Bacillus anthracis''
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===S6 in part of small ribosomal subunit===
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[[1qd7]] – TtRPS6+TtRPS4+TtRPS5+TtRPS7+TtRPS8+TtRPS15+TtRPS17+TtRPS20+16S RRNA fragment<br />
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**[[2kjv]] – TtRPS6 – NMR - ''Thermus thermophilus''<br />
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[[1g1x]] - TtRPS6+TtRPS15+TtRPS18+16S RRNA fragment<br />
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**[[2kjw]] – TtRPS6 (mutant) – NMR<br />
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[[3j16]] – yRPS6 + yRPS24 + yRPS30 + yRPL6 + yRPL10 + yRPL11 + 18S RRNA + 28SRRNA + P-site tRNA – yeast - Cryo EM
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**[[2bvz]], [[1ris]], [[3zzp]] – TtRPS6<br />
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**[[2bxj]], [[1cqm]], [[1cqn]], [[1qjh]], [[1lou]] - TtRPS6 (mutant)<br />
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[[6i6w]], [[6i6y]], [[7b8v]] – TtRPS6 circular permutation<br />
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[[6i69]], [[6i6e]], [[6i6i]], [[6i6o]], [[6i6s]], [[6i6u]] – TtRPS6 (mutant) circular permutation<br />
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**[[2j5a]] – RPS6 – ''Aquifex aeolicus''<br />
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**[[1vmb]] – RPS6 – ''Thermotoga maritima''<br />
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**[[3r3t]] – RPS6 – ''Bacillus anthracis''
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*Ribosomal protein S6 in part of small ribosomal subunit
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**[[1qd7]] – TtRPS6+TtRPS4+TtRPS5+TtRPS7+TtRPS8+TtRPS15+TtRPS17+TtRPS20+16S RRNA fragment<br />
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**[[1g1x]] - TtRPS6+TtRPS15+TtRPS18+16S RRNA fragment<br />
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**[[3j16]] – yRPS6 + yRPS24 + yRPS30 + yRPL6 + yRPL10 + yRPL11 + 18S RRNA + 28SRRNA + P-site tRNA – yeast - Cryo EM
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}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Ribosomal protein S6 (PDB code 2bvz)

Drag the structure with the mouse to rotate

3D Structures of Ribosomal protein S6

Updated on 01-March-2022

6i6w, 6i6y, 7b8v – TtRPS6 circular permutation
6i69, 6i6e, 6i6i, 6i6o, 6i6s, 6i6u – TtRPS6 (mutant) circular permutation

References

  1. ↑ Ruvinsky I, Meyuhas O. Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. Trends Biochem Sci. 2006 Jun;31(6):342-8. Epub 2006 May 6. PMID:16679021 doi:http://dx.doi.org/10.1016/j.tibs.2006.04.003

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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