Ribosomal protein S12

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[[Image:RPS12.png|left|200px|thumb|Crystal Structure of Ribosomal protein S12 from [[2zm6]], chain L]]
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<StructureSection load='1qzc' size='350' side='right' caption='Ribosomal protein S12 (aqua) complex with 16S RRNA helix 44 (grey), 23S RRNA helix 69 (green) and 23S RRNA SRL (pink) (PDB entry [[1qzc]])' scene=''>
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[[Ribosomal protein S12]] (RPS12) is one of the 22 proteins which belong to the small subunit of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]]. It is involved in the translation initiation step. The images at the left and at the right correspond to one representative RPS12, ''i.e.'' the crystal structure of Ribosomal protein S12 from ''Thermus thermophilus'' ([[2zm6]], chain L).
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[[Ribosomal protein S12]] (RPS12) is one of the 21 proteins which belong to the 30S small subunit of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]] or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. It is involved in the translation initiation step<ref>PMID:1725261</ref>.
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</StructureSection>
== 3D Structures of Ribosomal protein S12 ==
== 3D Structures of Ribosomal protein S12 ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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=== RPS12 ===
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*Ribosomal protein S12
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[[1qzc]] - TtRPS12+16S RRNA helix+23S RRNA helix - ''Thermus thermophilus'' <br />
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**[[1qzc]] - TtRPS12+16S RRNA helix+23S RRNA helix - ''Thermus thermophilus'' <br />
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[[1pn7]] – TtRPS12+TtRPL11+P-site tRNA+16S RRNA fragment+23S RRNA fragment<br />
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**[[1pn7]] – TtRPS12+TtRPL11+P-site tRNA+16S RRNA fragment+23S RRNA fragment<br />
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[[1pn8]] - TtRPS12+TtRPL11+E-site tRNA+16S RRNA fragment+23S RRNA fragment<br />
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**[[1pn8]] - TtRPS12+TtRPL11+E-site tRNA+16S RRNA fragment+23S RRNA fragment<br />
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[[1mvr]] – EcRPS12+EcRPL11+mRNA codon+16S RRNA fragment+23S RRNA fragment – Cryo-EM - ''Escherichia coli''<br />
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**[[1mvr]] – EcRPS12+EcRPL11+mRNA codon+16S RRNA fragment+23S RRNA fragment – Cryo-EM - ''Escherichia coli''<br />
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=== S12 in part of small ribosomal subunit ===
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*Ribosomal protein S12 in part of small ribosomal subunit
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[[3iy8]] - EcRPS12+EcRPS5+EcRPS6+EcRPS9+EcRPS9 EcRPS8+EcRPS11+EcRPS15+EcRPS16+EcRPS17+EcRPS18+''Leishmania taretolae'' mRNA<br />
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**[[3iy8]] - EcRPS12+EcRPS5+EcRPS6+EcRPS9+EcRPS9 EcRPS8+EcRPS11+EcRPS15+EcRPS16+EcRPS17+EcRPS18+''Leishmania taretolae'' mRNA<br />
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[[2r1g]] – TtRPS12+ TtRPS9+ TtRPS13+ 16S RRNA fragment<br />
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**[[1mj1]] - EcRPS12 +EcRPS13 +EcRPL11 + Phe-tRNA + elongation factor Tu + 23S RRNA fragments – Cryo EM<br />
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**[[3ep2]], [[3eq4]] - EcRPS12 +EcRPL11 + tRNA + elongation factor Tu + 16S RRNA fragments + 23S RRNA fragments – Cryo EM<br />
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**[[1zn1]] - EcRPS12 + ribosome recycling factor + 16S RRNA fragment + 23S RRNA fragments – Cryo EM<br />
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**[[3j0d]] - EcRPS12 + RPL11 + ribosome recycling factor + 16S RRNA fragment + 23S RRNA fragments – Cryo EM<br />
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**[[3j0e]] - EcRPS12 + elongation factor G + ribosome recycling factor + 16S RRNA fragment + 23S RRNA fragments – Cryo EM<br />
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**[[2r1g]] – TtRPS12+ TtRPS9+ TtRPS13+ 16S RRNA fragment<br />
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}}
==Related Structures and Topics==
==Related Structures and Topics==
*[[LepA]]
*[[LepA]]
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*For additional information, see: [[Translation]]
*For additional information, see: [[Translation]]
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Ribosomal protein S12 (aqua) complex with 16S RRNA helix 44 (grey), 23S RRNA helix 69 (green) and 23S RRNA SRL (pink) (PDB entry 1qzc)

Drag the structure with the mouse to rotate

3D Structures of Ribosomal protein S12

Updated on 16-August-2016

Related Structures and Topics


References

  1. ↑ O'Connor M, De Stasio EA, Dahlberg AE. Interaction between 16S ribosomal RNA and ribosomal protein S12: differential effects of paromomycin and streptomycin. Biochimie. 1991 Dec;73(12):1493-500. PMID:1725261

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