1fnz

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[[Image:1fnz.gif|left|200px]]<br /><applet load="1fnz" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1fnz, resolution 2.05&Aring;" />
 
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'''A bark lectin from robinia pseudoacacia in complex with N-acetylgalactosamine'''<br />
 
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==Overview==
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==A bark lectin from robinia pseudoacacia in complex with N-acetylgalactosamine==
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The structure of the bark lectin RPbAI (isoform A4) from Robinia pseudoacacia has been determined by protein crystallography both in the free form and complexed with N-acetylgalactosamine. The free form is refined at 1.80 A resolution to an R-factor of 18.9% whereas the complexed structure has an R-factor of 19.7% at 2.05 A resolution. Both structures are compared to each other and to other available legume lectin structures. The polypeptide chains of the two structures exhibit the characteristic legume lectin tertiary fold. The quaternary structure resembles that of the Phaseolus vulgaris lectin, the soybean agglutinin, and the Dolichos biflorus lectin, but displays some unique features leading to the extreme stability of this lectin.
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<StructureSection load='1fnz' size='340' side='right'caption='[[1fnz]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1fnz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Robinia_pseudoacacia Robinia pseudoacacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FNZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fnz OCA], [https://pdbe.org/1fnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fnz RCSB], [https://www.ebi.ac.uk/pdbsum/1fnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fnz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LCB1_ROBPS LCB1_ROBPS]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/1fnz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fnz ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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1FNZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Robinia_pseudoacacia Robinia pseudoacacia] with <scene name='pdbligand=A2G:'>A2G</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:A2g+Binding+Site+For+Residue+A+555'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+A+500'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNZ OCA].
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*[[Agglutinin 3D structures|Agglutinin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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Structure of a legume lectin from the bark of Robinia pseudoacacia and its complex with N-acetylgalactosamine., Rabijns A, Verboven C, Rouge P, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Proteins. 2001 Sep 1;44(4):470-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11484224 11484224]
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[[Category: Large Structures]]
[[Category: Robinia pseudoacacia]]
[[Category: Robinia pseudoacacia]]
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[[Category: Single protein]]
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[[Category: Barre A]]
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[[Category: Barre, A.]]
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[[Category: De Ranter CJ]]
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[[Category: Damme, E J.Van.]]
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[[Category: Peumans WJ]]
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[[Category: Peumans, W J.]]
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[[Category: Rabijns A]]
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[[Category: Rabijns, A.]]
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[[Category: Rouge P]]
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[[Category: Ranter, C J.De.]]
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[[Category: Van Damme EJ]]
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[[Category: Rouge, P.]]
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[[Category: Verboven C]]
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[[Category: Verboven, C.]]
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[[Category: A2G]]
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[[Category: CA]]
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[[Category: jelly roll]]
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[[Category: sugar binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Mar 14 09:41:46 2008''
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Current revision

A bark lectin from robinia pseudoacacia in complex with N-acetylgalactosamine

PDB ID 1fnz

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