This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2iwe

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:27, 13 December 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
==STRUCTURE OF A CAVITY MUTANT (H117G) OF PSEUDOMONAS AERUGINOSA AZURIN==
+
 
-
<StructureSection load='2iwe' size='340' side='right' caption='[[2iwe]], [[Resolution|resolution]] 2.83&Aring;' scene=''>
+
==Structure of a cavity mutant (H117G) of Pseudomonas aeruginosa azurin==
 +
<StructureSection load='2iwe' size='340' side='right'caption='[[2iwe]], [[Resolution|resolution]] 2.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
[[2iwe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWE OCA]. <br>
+
<table><tr><td colspan='2'>[[2iwe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IWE FirstGlance]. <br>
-
<b>[[Ligand|Ligands:]]</b> <scene name='pdbligand=2IH:1,1-HEXANE-1,6-DIYLBIS(1H-IMIDAZOLE)'>2IH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.83&#8491;</td></tr>
-
<b>[[Related_structure|Related:]]</b> [[1ag0|1ag0]], [[1azn|1azn]], [[1azr|1azr]], [[1azu|1azu]], [[1bex|1bex]], [[1cc3|1cc3]], [[1e5y|1e5y]], [[1e5z|1e5z]], [[1e65|1e65]], [[1e67|1e67]], [[1etj|1etj]], [[1ezl|1ezl]], [[1gr7|1gr7]], [[1i53|1i53]], [[1ils|1ils]], [[1ilu|1ilu]], [[1jvl|1jvl]], [[1jvo|1jvo]], [[1jze|1jze]], [[1jzf|1jzf]], [[1jzg|1jzg]], [[1jzh|1jzh]], [[1jzi|1jzi]], [[1jzj|1jzj]], [[1nzr|1nzr]], [[1r1c|1r1c]], [[1vlx|1vlx]], [[1xb3|1xb3]], [[1xb6|1xb6]], [[1xb8|1xb8]], [[2azu|2azu]], [[2tsa|2tsa]], [[2tsb|2tsb]], [[3azu|3azu]], [[4azu|4azu]], [[5azu|5azu]]<br>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2IH:1,1-HEXANE-1,6-DIYLBIS(1H-IMIDAZOLE)'>2IH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwe OCA], [https://pdbe.org/2iwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iwe RCSB], [https://www.ebi.ac.uk/pdbsum/2iwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwe ProSAT]</span></td></tr>
-
<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iwe RCSB], [http://www.ebi.ac.uk/pdbsum/2iwe PDBsum]</span><br>
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE] Transfers electrons from cytochrome c551 to cytochrome oxidase.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
-
[[Image:Consurf_key_small.gif|right]]
+
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/2iwe_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/2iwe_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iwe ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
-
== References ==
+
 
-
<references/>
+
==See Also==
 +
*[[Azurin 3D structures|Azurin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
-
[[Category: Canters, G W.]]
+
[[Category: Canters GW]]
-
[[Category: Jongh, T E.De.]]
+
[[Category: De Jongh TE]]
-
[[Category: Prudencio, M.]]
+
[[Category: Prudencio M]]
-
[[Category: Roon, A M.M Van.]]
+
[[Category: Ubbink M]]
-
[[Category: Ubbink, M.]]
+
[[Category: Van Roon AMM]]
-
[[Category: Azurin]]
+
-
[[Category: Blue copper protein]]
+
-
[[Category: Electron transport]]
+
-
[[Category: Metal-binding]]
+
-
[[Category: Periplasmic]]
+
-
[[Category: Redox protein]]
+
-
[[Category: Transport]]
+

Current revision

Structure of a cavity mutant (H117G) of Pseudomonas aeruginosa azurin

PDB ID 2iwe

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools