4cbx

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==Crystal structure of Plasmodium berghei actin II==
==Crystal structure of Plasmodium berghei actin II==
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<StructureSection load='4cbx' size='340' side='right' caption='[[4cbx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='4cbx' size='340' side='right'caption='[[4cbx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cbx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CBX OCA]. <br>
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<table><tr><td colspan='2'>[[4cbx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Plasmodium_berghei Plasmodium berghei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CBX FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cbu|4cbu]], [[4cbw|4cbw]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cbx OCA], [https://pdbe.org/4cbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cbx RCSB], [https://www.ebi.ac.uk/pdbsum/4cbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cbx ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cbx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cbx RCSB], [http://www.ebi.ac.uk/pdbsum/4cbx PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACT2_PLABA ACT2_PLABA] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural differences explain diverse functions of Plasmodium actins.,Vahokoski J, Bhargav SP, Desfosses A, Andreadaki M, Kumpula EP, Martinez SM, Ignatev A, Lepper S, Frischknecht F, Siden-Kiamos I, Sachse C, Kursula I PLoS Pathog. 2014 Apr 17;10(4):e1004091. doi: 10.1371/journal.ppat.1004091., eCollection 2014 Apr. PMID:24743229<ref>PMID:24743229</ref>
Structural differences explain diverse functions of Plasmodium actins.,Vahokoski J, Bhargav SP, Desfosses A, Andreadaki M, Kumpula EP, Martinez SM, Ignatev A, Lepper S, Frischknecht F, Siden-Kiamos I, Sachse C, Kursula I PLoS Pathog. 2014 Apr 17;10(4):e1004091. doi: 10.1371/journal.ppat.1004091., eCollection 2014 Apr. PMID:24743229<ref>PMID:24743229</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>== References ==
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</div>
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<div class="pdbe-citations 4cbx" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Actin 3D structures|Actin 3D structures]]
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*[[Gelsolin 3D structures|Gelsolin 3D structures]]
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== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Andreadaki, M.]]
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[[Category: Large Structures]]
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[[Category: Bhargav, S P.]]
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[[Category: Mus musculus]]
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[[Category: Desfosses, A.]]
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[[Category: Plasmodium berghei]]
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[[Category: Frischknecht, F.]]
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[[Category: Andreadaki M]]
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[[Category: Ignatev, A.]]
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[[Category: Bhargav SP]]
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[[Category: Kumpula, E P.]]
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[[Category: Desfosses A]]
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[[Category: Kursula, I.]]
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[[Category: Frischknecht F]]
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[[Category: Lepper, S.]]
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[[Category: Ignatev A]]
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[[Category: Martinez, S Munico.]]
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[[Category: Kumpula EP]]
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[[Category: Sachse, C.]]
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[[Category: Kursula I]]
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[[Category: Siden-Kiamos, I.]]
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[[Category: Lepper S]]
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[[Category: Vahokoski, J.]]
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[[Category: Munico Martinez S]]
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[[Category: Malaria]]
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[[Category: Sachse C]]
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[[Category: Motility]]
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[[Category: Siden-Kiamos I]]
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[[Category: Motor protein]]
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[[Category: Vahokoski J]]
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[[Category: Parasite]]
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Current revision

Crystal structure of Plasmodium berghei actin II

PDB ID 4cbx

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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