3wgm

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==STAPHYLOCOCCUS AUREUS FTSZ T7 mutant substituted for GAN bound with GTP, DeltaT7GAN-GTP==
==STAPHYLOCOCCUS AUREUS FTSZ T7 mutant substituted for GAN bound with GTP, DeltaT7GAN-GTP==
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<StructureSection load='3wgm' size='340' side='right' caption='[[3wgm]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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<StructureSection load='3wgm' size='340' side='right'caption='[[3wgm]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3wgm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WGM OCA]. <br>
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<table><tr><td colspan='2'>[[3wgm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WGM FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.091&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3voa|3voa]], [[3wgj|3wgj]], [[3wgk|3wgk]], [[3wgl|3wgl]], [[3wgn|3wgn]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ftsZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wgm OCA], [https://pdbe.org/3wgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wgm RCSB], [https://www.ebi.ac.uk/pdbsum/3wgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wgm ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wgm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wgm RCSB], [http://www.ebi.ac.uk/pdbsum/3wgm PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/FTSZ_STAAM FTSZ_STAAM] Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural change in FtsZ Induced by intermolecular interactions between bound GTP and the T7 loop.,Matsui T, Han X, Yu J, Yao M, Tanaka I J Biol Chem. 2014 Feb 7;289(6):3501-9. doi: 10.1074/jbc.M113.514901. Epub 2013, Dec 17. PMID:24347164<ref>PMID:24347164</ref>
Structural change in FtsZ Induced by intermolecular interactions between bound GTP and the T7 loop.,Matsui T, Han X, Yu J, Yao M, Tanaka I J Biol Chem. 2014 Feb 7;289(6):3501-9. doi: 10.1074/jbc.M113.514901. Epub 2013, Dec 17. PMID:24347164<ref>PMID:24347164</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3wgm" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Cell division protein 3D structures|Cell division protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Staam]]
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[[Category: Large Structures]]
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[[Category: Han, X.]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Matsui, T.]]
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[[Category: Han X]]
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[[Category: Tanaka, I.]]
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[[Category: Matsui T]]
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[[Category: Yao, M.]]
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[[Category: Tanaka I]]
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[[Category: Yu, J.]]
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[[Category: Yao M]]
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[[Category: Cell cycle]]
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[[Category: Yu J]]
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[[Category: Cell division]]
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[[Category: Ftsz]]
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[[Category: Gtp-binding]]
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[[Category: Gtpase]]
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[[Category: Polymerization]]
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[[Category: Tubulin homolog]]
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Current revision

STAPHYLOCOCCUS AUREUS FTSZ T7 mutant substituted for GAN bound with GTP, DeltaT7GAN-GTP

PDB ID 3wgm

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