2iez

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==Crystal Structure of mouse Rab27b bound to GDP in monoclinic space group==
==Crystal Structure of mouse Rab27b bound to GDP in monoclinic space group==
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<StructureSection load='2iez' size='340' side='right' caption='[[2iez]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='2iez' size='340' side='right'caption='[[2iez]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2iez]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEZ OCA]. <br>
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<table><tr><td colspan='2'>[[2iez]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IEZ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iey|2iey]], [[2if0|2if0]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iez OCA], [https://pdbe.org/2iez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iez RCSB], [https://www.ebi.ac.uk/pdbsum/2iez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iez ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iez OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iez RCSB], [http://www.ebi.ac.uk/pdbsum/2iez PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/RB27B_MOUSE RB27B_MOUSE] May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/2iez_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/2iez_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iez ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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Structure of the small GTPase Rab27b shows an unexpected swapped dimer.,Chavas LM, Torii S, Kamikubo H, Kawasaki M, Ihara K, Kato R, Kataoka M, Izumi T, Wakatsuki S Acta Crystallogr D Biol Crystallogr. 2007 Jul;63(Pt 7):769-79. Epub 2007 Jun 15. PMID:17582168<ref>PMID:17582168</ref>
Structure of the small GTPase Rab27b shows an unexpected swapped dimer.,Chavas LM, Torii S, Kamikubo H, Kawasaki M, Ihara K, Kato R, Kataoka M, Izumi T, Wakatsuki S Acta Crystallogr D Biol Crystallogr. 2007 Jul;63(Pt 7):769-79. Epub 2007 Jun 15. PMID:17582168<ref>PMID:17582168</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2iez" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Small monomeric GTPase]]
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[[Category: Chavas LMG]]
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[[Category: Chavas, L M.G.]]
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[[Category: Ihara K]]
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[[Category: Ihara, K.]]
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[[Category: Izumi T]]
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[[Category: Izumi, T.]]
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[[Category: Kamikubo H]]
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[[Category: Kamikubo, H.]]
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[[Category: Kataoka M]]
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[[Category: Kataoka, M.]]
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[[Category: Kato R]]
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[[Category: Kato, R.]]
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[[Category: Kawasaki M]]
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[[Category: Kawasaki, M.]]
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[[Category: Torii S]]
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[[Category: Torii, S.]]
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[[Category: Wakatsuki S]]
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[[Category: Wakatsuki, S.]]
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[[Category: Gdp]]
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[[Category: Gtpase]]
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[[Category: Rab]]
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[[Category: Rab27]]
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[[Category: Signaling protein]]
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[[Category: Swapping]]
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Current revision

Crystal Structure of mouse Rab27b bound to GDP in monoclinic space group

PDB ID 2iez

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Proteopedia Page Contributors and Editors (what is this?)

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