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4cjm
From Proteopedia
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==Crystal structure of human FGF18== | ==Crystal structure of human FGF18== | ||
| - | <StructureSection load='4cjm' size='340' side='right' caption='[[4cjm]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='4cjm' size='340' side='right'caption='[[4cjm]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4cjm]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4cjm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CJM FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| - | <tr><td class="sblockLbl"><b> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cjm OCA], [https://pdbe.org/4cjm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cjm RCSB], [https://www.ebi.ac.uk/pdbsum/4cjm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cjm ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FGF18_HUMAN FGF18_HUMAN] Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.<ref>PMID:16597617</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Adam LE]] |
| - | [[Category: | + | [[Category: Blundell TL]] |
| - | [[Category: | + | [[Category: Brown A]] |
| - | + | ||
Current revision
Crystal structure of human FGF18
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