2w9r

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==STRUCTURAL BASIS OF N-END RULE SUBSTRATE RECOGNITION IN ESCHERICHIA COLI BY THE CLPAP ADAPTOR PROTEIN CLPS==
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<StructureSection load='2w9r' size='340' side='right' caption='[[2w9r]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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==Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS==
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<StructureSection load='2w9r' size='340' side='right'caption='[[2w9r]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w9r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9R OCA]. <br>
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<table><tr><td colspan='2'>[[2w9r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9R FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lzw|1lzw]], [[1mbu|1mbu]], [[1jre|1jre]], [[1l8h|1l8h]], [[1mg9|1mg9]], [[1mbv|1mbv]], [[1l8i|1l8i]], [[1r6o|1r6o]], [[1jts|1jts]], [[1f33|1f33]], [[1f30|1f30]], [[1r6q|1r6q]], [[1mbx|1mbx]], [[1dps|1dps]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9r OCA], [https://pdbe.org/2w9r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9r RCSB], [https://www.ebi.ac.uk/pdbsum/2w9r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9r ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9r RCSB], [http://www.ebi.ac.uk/pdbsum/2w9r PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/CLPS_ECOLI CLPS_ECOLI] Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9r_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9r_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w9r ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS.,Schuenemann VJ, Kralik SM, Albrecht R, Spall SK, Truscott KN, Dougan DA, Zeth K EMBO Rep. 2009 May;10(5):508-14. Epub 2009 Apr 17. PMID:19373253<ref>PMID:19373253</ref>
Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS.,Schuenemann VJ, Kralik SM, Albrecht R, Spall SK, Truscott KN, Dougan DA, Zeth K EMBO Rep. 2009 May;10(5):508-14. Epub 2009 Apr 17. PMID:19373253<ref>PMID:19373253</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2w9r" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[ATP-dependent Clp protease adaptor protein 3D structures|ATP-dependent Clp protease adaptor protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Albrecht, R.]]
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[[Category: Large Structures]]
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[[Category: Dougan, D A.]]
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[[Category: Albrecht R]]
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[[Category: Kralik, S M.]]
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[[Category: Dougan DA]]
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[[Category: Schuenemann, V.]]
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[[Category: Kralik SM]]
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[[Category: Spall, S K.]]
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[[Category: Schuenemann V]]
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[[Category: Truscott, K N.]]
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[[Category: Spall SK]]
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[[Category: Zeth, K.]]
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[[Category: Truscott KN]]
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[[Category: Adaptor protein]]
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[[Category: Zeth K]]
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[[Category: Chaperone]]
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[[Category: Clpa]]
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[[Category: Clp]]
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[[Category: Dna condensation]]
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[[Category: Dna-binding]]
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[[Category: Iron]]
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[[Category: Iron storage]]
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[[Category: Metal-binding]]
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[[Category: N-end rule]]
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[[Category: Oxidoreductase]]
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Current revision

Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS

PDB ID 2w9r

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