2r5b
From Proteopedia
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==Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7== | ==Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7== | ||
| - | <StructureSection load='2r5b' size='340' side='right' caption='[[2r5b]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='2r5b' size='340' side='right'caption='[[2r5b]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2r5b]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5B OCA]. < | + | <table><tr><td colspan='2'>[[2r5b]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R5B FirstGlance]. <br> |
| - | </ | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DAS:D-ASPARTIC+ACID'>DAS</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=DGN:D-GLUTAMINE'>DGN</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5b OCA], [https://pdbe.org/2r5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r5b RCSB], [https://www.ebi.ac.uk/pdbsum/2r5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r5b ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | <tr | + | |
| - | + | ||
| - | <table> | + | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Potent D-peptide inhibitors of HIV-1 entry.,Welch BD, VanDemark AP, Heroux A, Hill CP, Kay MS Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16828-33. Epub 2007 Oct 17. PMID:17942675<ref>PMID:17942675</ref> | Potent D-peptide inhibitors of HIV-1 entry.,Welch BD, VanDemark AP, Heroux A, Hill CP, Kay MS Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16828-33. Epub 2007 Oct 17. PMID:17942675<ref>PMID:17942675</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | <div class="pdbe-citations 2r5b" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Gp41 3D Structures|Gp41 3D Structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Synthetic construct]] |
| - | [[Category: | + | [[Category: Heroux A]] |
| - | + | [[Category: Hill CP]] | |
| - | [[Category: | + | [[Category: Kay MS]] |
| - | [[Category: | + | [[Category: VanDemark AP]] |
| - | [[Category: | + | [[Category: Welch B]] |
| - | [[Category: | + | |
| - | + | ||
Current revision
Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7
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