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2uwf

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==Crystal structure of family 10 xylanase from Bacillus halodurans==
==Crystal structure of family 10 xylanase from Bacillus halodurans==
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<StructureSection load='2uwf' size='340' side='right' caption='[[2uwf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='2uwf' size='340' side='right'caption='[[2uwf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2uwf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UWF OCA]. <br>
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<table><tr><td colspan='2'>[[2uwf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans Alkalihalobacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UWF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uwf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uwf RCSB], [http://www.ebi.ac.uk/pdbsum/2uwf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uwf OCA], [https://pdbe.org/2uwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uwf RCSB], [https://www.ebi.ac.uk/pdbsum/2uwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uwf ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/XYNA_HALH5 XYNA_HALH5]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/2uwf_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/2uwf_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2uwf ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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An alkaline active xylanase: insights into mechanisms of high pH catalytic adaptation.,Mamo G, Thunnissen M, Hatti-Kaul R, Mattiasson B Biochimie. 2009 Sep;91(9):1187-96. Epub 2009 Jun 28. PMID:19567261<ref>PMID:19567261</ref>
An alkaline active xylanase: insights into mechanisms of high pH catalytic adaptation.,Mamo G, Thunnissen M, Hatti-Kaul R, Mattiasson B Biochimie. 2009 Sep;91(9):1187-96. Epub 2009 Jun 28. PMID:19567261<ref>PMID:19567261</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2uwf" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus halodurans]]
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[[Category: Alkalihalobacillus halodurans]]
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[[Category: Endo-1,4-beta-xylanase]]
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[[Category: Large Structures]]
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[[Category: Hatti-Kaul, R.]]
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[[Category: Hatti-Kaul R]]
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[[Category: Mamo, G.]]
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[[Category: Mamo G]]
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[[Category: Mattiasson, B.]]
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[[Category: Mattiasson B]]
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[[Category: Thunnissen, M.]]
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[[Category: Thunnissen M]]
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[[Category: Alkaline adaptation]]
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[[Category: Alkaliphilic]]
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[[Category: Bacillus haloduran]]
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[[Category: Endoxylanase]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Xylan degradation]]
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[[Category: Xylanase structure]]
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Current revision

Crystal structure of family 10 xylanase from Bacillus halodurans

PDB ID 2uwf

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