2nu3
From Proteopedia
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| - | [[Image:2nu3.gif|left|200px]]<br /><applet load="2nu3" size="350" color="white" frame="true" align="right" caption="2nu3, resolution 1.8Å" /> | ||
| - | '''Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I'''<br /> | ||
| - | == | + | ==Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I== |
| - | + | <StructureSection load='2nu3' size='340' side='right'caption='[[2nu3]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2nu3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo] and [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NU3 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu3 OCA], [https://pdbe.org/2nu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nu3 RCSB], [https://www.ebi.ac.uk/pdbsum/2nu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nu3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PRTB_STRGR PRTB_STRGR] Has a primary specificity for large aliphatic or aromatic amino acids. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nu3_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nu3 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Proteinase 3D structures|Proteinase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Meleagris gallopavo]] | [[Category: Meleagris gallopavo]] | ||
| - | [[Category: Protein complex]] | ||
| - | [[Category: Streptogrisin B]] | ||
[[Category: Streptomyces griseus]] | [[Category: Streptomyces griseus]] | ||
| - | [[Category: Anderson | + | [[Category: Anderson S]] |
| - | [[Category: Bateman | + | [[Category: Bateman KS]] |
| - | [[Category: Huang | + | [[Category: Huang K]] |
| - | [[Category: James | + | [[Category: James MNG]] |
| - | [[Category: Jr | + | [[Category: Laskowski Jr M]] |
| - | [[Category: Lu | + | [[Category: Lu W]] |
| - | [[Category: Qasim | + | [[Category: Qasim MA]] |
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Current revision
Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
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