2wnr

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==The structure of Methanothermobacter thermautotrophicus exosome core assembly==
==The structure of Methanothermobacter thermautotrophicus exosome core assembly==
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<StructureSection load='2wnr' size='340' side='right' caption='[[2wnr]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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<StructureSection load='2wnr' size='340' side='right'caption='[[2wnr]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wnr]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNR OCA]. <br>
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<table><tr><td colspan='2'>[[2wnr]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wnr RCSB], [http://www.ebi.ac.uk/pdbsum/2wnr PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnr OCA], [https://pdbe.org/2wnr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wnr RCSB], [https://www.ebi.ac.uk/pdbsum/2wnr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnr ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RRP42_METTH RRP42_METTH] Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.[HAMAP-Rule:MF_00622]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wnr_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wnr_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wnr ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring.,Ng CL, Waterman DG, Antson AA, Ortiz-Lombardia M Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):522-8. Epub 2010, Apr 21. PMID:20445227<ref>PMID:20445227</ref>
Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring.,Ng CL, Waterman DG, Antson AA, Ortiz-Lombardia M Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):522-8. Epub 2010, Apr 21. PMID:20445227<ref>PMID:20445227</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2wnr" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: Antson, A A.]]
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[[Category: Antson AA]]
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[[Category: Ng, C L.]]
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[[Category: Ng CL]]
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[[Category: Ortiz-Lombardia, M.]]
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[[Category: Ortiz-Lombardia M]]
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[[Category: Waterman, D G.]]
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[[Category: Waterman DG]]
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[[Category: 3'-5' exoribonuclease]]
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[[Category: Exonuclease]]
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[[Category: Exosome]]
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[[Category: Hydrolase]]
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[[Category: Nuclease]]
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[[Category: Phosphate binding]]
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Current revision

The structure of Methanothermobacter thermautotrophicus exosome core assembly

PDB ID 2wnr

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