2onq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2onq" [edit=sysop:move=sysop])
Current revision (10:45, 30 August 2023) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Gbeta1 stabilization by in vitro evolution and computational design==
==Gbeta1 stabilization by in vitro evolution and computational design==
-
<StructureSection load='2onq' size='340' side='right' caption='[[2onq]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+
<StructureSection load='2onq' size='340' side='right'caption='[[2onq]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2onq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_sp._g148 Streptococcus sp. g148]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONQ OCA]. <br>
+
<table><tr><td colspan='2'>[[2onq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_sp._G148 Streptococcus sp. G148]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ONQ FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2on8|2on8]], [[1pga|1pga]], [[1gb4|1gb4]], [[1fcc|1fcc]], [[3gb1|3gb1]], [[1p7e|1p7e]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">spg ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1324 Streptococcus sp. G148])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2onq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2onq OCA], [https://pdbe.org/2onq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2onq RCSB], [https://www.ebi.ac.uk/pdbsum/2onq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2onq ProSAT]</span></td></tr>
-
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
+
</table>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2onq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2onq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2onq RCSB], [http://www.ebi.ac.uk/pdbsum/2onq PDBsum]</span></td></tr>
+
== Function ==
-
<table>
+
[https://www.uniprot.org/uniprot/SPG2_STRSG SPG2_STRSG]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2onq_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2onq_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2onq ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 24: Line 25:
Optimization of the gbeta1 domain by computational design and by in vitro evolution: structural and energetic basis of stabilization.,Wunderlich M, Max KE, Roske Y, Mueller U, Heinemann U, Schmid FX J Mol Biol. 2007 Oct 26;373(3):775-84. Epub 2007 Aug 19. PMID:17868696<ref>PMID:17868696</ref>
Optimization of the gbeta1 domain by computational design and by in vitro evolution: structural and energetic basis of stabilization.,Wunderlich M, Max KE, Roske Y, Mueller U, Heinemann U, Schmid FX J Mol Biol. 2007 Oct 26;373(3):775-84. Epub 2007 Aug 19. PMID:17868696<ref>PMID:17868696</ref>
-
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2onq" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Protein G|Protein G]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Streptococcus sp. g148]]
+
[[Category: Large Structures]]
-
[[Category: Heinemann, U.]]
+
[[Category: Streptococcus sp. G148]]
-
[[Category: Max, K E.A.]]
+
[[Category: Heinemann U]]
-
[[Category: Alpha helix]]
+
[[Category: Max KEA]]
-
[[Category: Beta sheet]]
+
-
[[Category: Improved hydrophobic packing of core residue]]
+
-
[[Category: Protein binding]]
+

Current revision

Gbeta1 stabilization by in vitro evolution and computational design

PDB ID 2onq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2onq"
Personal tools