2wkf
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='2wkf' size='340' side='right' caption='[[2wkf]], [[Resolution|resolution]] 2.05Å' scene=''> | + | ==Crystal Structure of Macrophage Migration Inhibitory Factor from Plasmodium falciparum== |
| + | <StructureSection load='2wkf' size='340' side='right'caption='[[2wkf]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2wkf]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2wkf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WKF FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wkf OCA], [https://pdbe.org/2wkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wkf RCSB], [https://www.ebi.ac.uk/pdbsum/2wkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wkf ProSAT]</span></td></tr> | |
| - | <tr | + | </table> |
| - | + | == Function == | |
| - | <table> | + | [https://www.uniprot.org/uniprot/Q8I5C5_PLAF7 Q8I5C5_PLAF7] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/2wkf_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/2wkf_consurf.spt"</scriptWhenChecked> |
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wkf ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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The crystal structures of macrophage migration inhibition factor (MIF) from Plasmodium falciparum and Plasmodium berghei.,Dobson SE, Augustijn KD, Brannigan JA, Schnick C, Janse CJ, Dodson EJ, Waters AP, Wilkinson AJ Protein Sci. 2009 Oct 13. PMID:19827093<ref>PMID:19827093</ref> | The crystal structures of macrophage migration inhibition factor (MIF) from Plasmodium falciparum and Plasmodium berghei.,Dobson SE, Augustijn KD, Brannigan JA, Schnick C, Janse CJ, Dodson EJ, Waters AP, Wilkinson AJ Protein Sci. 2009 Oct 13. PMID:19827093<ref>PMID:19827093</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | <div class="pdbe-citations 2wkf" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Macrophage inhibitory factor 3D structures|Macrophage inhibitory factor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Plasmodium falciparum]] | + | [[Category: Large Structures]] |
| - | [[Category: Augustijn | + | [[Category: Plasmodium falciparum 3D7]] |
| - | [[Category: Brannigan | + | [[Category: Augustijn KD]] |
| - | [[Category: Dobson | + | [[Category: Brannigan JA]] |
| - | [[Category: Dodson | + | [[Category: Dobson SE]] |
| - | [[Category: Waters | + | [[Category: Dodson EJ]] |
| - | [[Category: Wilkinson | + | [[Category: Waters AP]] |
| - | + | [[Category: Wilkinson AJ]] | |
Current revision
Crystal Structure of Macrophage Migration Inhibitory Factor from Plasmodium falciparum
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