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4nw9

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==Crystal structure of macrocycles containing Abeta17-23 (LVF(MEA)AED) and Abeta30-36 (AIIGL(ORN)V)==
==Crystal structure of macrocycles containing Abeta17-23 (LVF(MEA)AED) and Abeta30-36 (AIIGL(ORN)V)==
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<StructureSection load='4nw9' size='340' side='right' caption='[[4nw9]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
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<StructureSection load='4nw9' size='340' side='right'caption='[[4nw9]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nw9]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NW9 OCA]. <br>
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<table><tr><td colspan='2'>[[4nw9]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NW9 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MEA:N-METHYLPHENYLALANINE'>MEA</scene>, <scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MEA:N-METHYLPHENYLALANINE'>MEA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ntp|4ntp]], [[4ntr|4ntr]], [[4nw8|4nw8]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nw9 OCA], [https://pdbe.org/4nw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nw9 RCSB], [https://www.ebi.ac.uk/pdbsum/4nw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nw9 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nw9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nw9 RCSB], [http://www.ebi.ac.uk/pdbsum/4nw9 PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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X-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Abeta,Spencer RK, Li H, Nowick JS J Am Chem Soc. 2014 Apr 3. PMID:24669800<ref>PMID:24669800</ref>
X-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Abeta,Spencer RK, Li H, Nowick JS J Am Chem Soc. 2014 Apr 3. PMID:24669800<ref>PMID:24669800</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4nw9" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Li, H.]]
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[[Category: Large Structures]]
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[[Category: Nowick, J S.]]
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[[Category: Synthetic construct]]
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[[Category: Spencer, R K.]]
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[[Category: Li H]]
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[[Category: Amyloid]]
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[[Category: Nowick JS]]
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[[Category: Beta-hairpin]]
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[[Category: Spencer RK]]
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[[Category: Beta-sheet]]
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[[Category: De novo protein]]
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[[Category: Protein binding]]
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Current revision

Crystal structure of macrocycles containing Abeta17-23 (LVF(MEA)AED) and Abeta30-36 (AIIGL(ORN)V)

PDB ID 4nw9

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