4cbw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:07, 20 December 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of Plasmodium berghei actin I with D-loop from muscle actin==
==Crystal structure of Plasmodium berghei actin I with D-loop from muscle actin==
-
<StructureSection load='4cbw' size='340' side='right' caption='[[4cbw]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+
<StructureSection load='4cbw' size='340' side='right'caption='[[4cbw]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4cbw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Plabe Plabe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CBW OCA]. <br>
+
<table><tr><td colspan='2'>[[4cbw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus], [https://en.wikipedia.org/wiki/Plasmodium_berghei Plasmodium berghei] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CBW FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene><br>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.501&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cbu|4cbu]], [[4cbx|4cbx]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene></td></tr>
-
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cbw OCA], [https://pdbe.org/4cbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cbw RCSB], [https://www.ebi.ac.uk/pdbsum/4cbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cbw ProSAT]</span></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cbw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cbw RCSB], [http://www.ebi.ac.uk/pdbsum/4cbw PDBsum]</span></td></tr>
+
</table>
-
<table>
+
== Function ==
 +
[https://www.uniprot.org/uniprot/ACT1_PLABA ACT1_PLABA] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.[https://www.uniprot.org/uniprot/ACTS_PIG ACTS_PIG] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 14: Line 16:
Structural differences explain diverse functions of Plasmodium actins.,Vahokoski J, Bhargav SP, Desfosses A, Andreadaki M, Kumpula EP, Martinez SM, Ignatev A, Lepper S, Frischknecht F, Siden-Kiamos I, Sachse C, Kursula I PLoS Pathog. 2014 Apr 17;10(4):e1004091. doi: 10.1371/journal.ppat.1004091., eCollection 2014 Apr. PMID:24743229<ref>PMID:24743229</ref>
Structural differences explain diverse functions of Plasmodium actins.,Vahokoski J, Bhargav SP, Desfosses A, Andreadaki M, Kumpula EP, Martinez SM, Ignatev A, Lepper S, Frischknecht F, Siden-Kiamos I, Sachse C, Kursula I PLoS Pathog. 2014 Apr 17;10(4):e1004091. doi: 10.1371/journal.ppat.1004091., eCollection 2014 Apr. PMID:24743229<ref>PMID:24743229</ref>
-
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4cbw" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Actin 3D structures|Actin 3D structures]]
 +
*[[Gelsolin 3D structures|Gelsolin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Large Structures]]
-
[[Category: Plabe]]
+
[[Category: Mus musculus]]
-
[[Category: Andreadaki, M.]]
+
[[Category: Plasmodium berghei]]
-
[[Category: Bhargav, S P.]]
+
[[Category: Synthetic construct]]
-
[[Category: Desfosses, A.]]
+
[[Category: Andreadaki M]]
-
[[Category: Frischknecht, F.]]
+
[[Category: Bhargav SP]]
-
[[Category: Ignatev, A.]]
+
[[Category: Desfosses A]]
-
[[Category: Kumpula, E P.]]
+
[[Category: Frischknecht F]]
-
[[Category: Kursula, I.]]
+
[[Category: Ignatev A]]
-
[[Category: Lepper, S.]]
+
[[Category: Kumpula EP]]
-
[[Category: Martinez, S Munico.]]
+
[[Category: Kursula I]]
-
[[Category: Sachse, C.]]
+
[[Category: Lepper S]]
-
[[Category: Siden-Kiamos, I.]]
+
[[Category: Munico Martinez S]]
-
[[Category: Vahokoski, J.]]
+
[[Category: Sachse C]]
-
[[Category: Malaria]]
+
[[Category: Siden-Kiamos I]]
-
[[Category: Motility]]
+
[[Category: Vahokoski J]]
-
[[Category: Motor protein]]
+
-
[[Category: Parasite]]
+

Current revision

Crystal structure of Plasmodium berghei actin I with D-loop from muscle actin

PDB ID 4cbw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools