2md9

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==Solution Structure of an Active Site Mutant Pepitdyl Carrier Protein==
==Solution Structure of an Active Site Mutant Pepitdyl Carrier Protein==
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<StructureSection load='2md9' size='340' side='right' caption='[[2md9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2md9' size='340' side='right'caption='[[2md9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2md9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_10027 Atcc 10027]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MD9 OCA]. <br>
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<table><tr><td colspan='2'>[[2md9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MD9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MD9 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gdy|2gdy]], [[2gdx|2gdx]], [[2gdw|2gdw]], [[2ge1|2ge1]], [[1dny|1dny]], [[4mrt|4mrt]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tycC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=54914 ATCC 10027])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2md9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2md9 OCA], [https://pdbe.org/2md9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2md9 RCSB], [https://www.ebi.ac.uk/pdbsum/2md9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2md9 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2md9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2md9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2md9 RCSB], [http://www.ebi.ac.uk/pdbsum/2md9 PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/TYCC_BREPA TYCC_BREPA] Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification.,Tufar P, Rahighi S, Kraas FI, Kirchner DK, Lohr F, Henrich E, Kopke J, Dikic I, Guntert P, Marahiel MA, Dotsch V Chem Biol. 2014 Apr 2. pii: S1074-5521(14)00073-8. doi:, 10.1016/j.chembiol.2014.02.014. PMID:24704508<ref>PMID:24704508</ref>
Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification.,Tufar P, Rahighi S, Kraas FI, Kirchner DK, Lohr F, Henrich E, Kopke J, Dikic I, Guntert P, Marahiel MA, Dotsch V Chem Biol. 2014 Apr 2. pii: S1074-5521(14)00073-8. doi:, 10.1016/j.chembiol.2014.02.014. PMID:24704508<ref>PMID:24704508</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2md9" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 10027]]
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[[Category: Brevibacillus parabrevis]]
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[[Category: Dikic, I.]]
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[[Category: Large Structures]]
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[[Category: Doetsch, V.]]
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[[Category: Dikic I]]
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[[Category: Guentert, P.]]
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[[Category: Doetsch V]]
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[[Category: Henrich, E.]]
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[[Category: Guentert P]]
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[[Category: Kirchner, D K.]]
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[[Category: Henrich E]]
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[[Category: Koepke, J.]]
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[[Category: Kirchner DK]]
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[[Category: Kraas, F I.]]
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[[Category: Koepke J]]
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[[Category: Loehr, F.]]
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[[Category: Kraas FI]]
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[[Category: Marahiel, M A.]]
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[[Category: Loehr F]]
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[[Category: Rahighi, S.]]
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[[Category: Marahiel MA]]
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[[Category: Tufar, P.]]
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[[Category: Rahighi S]]
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[[Category: Carrier protein]]
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[[Category: Tufar P]]
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[[Category: Ligase]]
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[[Category: Protein]]
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Current revision

Solution Structure of an Active Site Mutant Pepitdyl Carrier Protein

PDB ID 2md9

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