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2xzr

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==ESCHERICHIA COLI IMMUNOGLOBULIN-BINDING PROTEIN EIBD 391-438 FUSED TO GCN4 ADAPTORS==
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<StructureSection load='2xzr' size='340' side='right' caption='[[2xzr]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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==Escherichia coli Immunoglobulin-binding protein EibD 391-438 FUSED TO GCN4 ADAPTORS==
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<StructureSection load='2xzr' size='340' side='right'caption='[[2xzr]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xzr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZR OCA]. <br>
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<table><tr><td colspan='2'>[[2xzr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_P-EibD Enterobacteria phage P-EibD]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XZR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xqh|2xqh]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xzr OCA], [https://pdbe.org/2xzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xzr RCSB], [https://www.ebi.ac.uk/pdbsum/2xzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xzr ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xzr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xzr RCSB], [http://www.ebi.ac.uk/pdbsum/2xzr PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/EIBD_ECOLX EIBD_ECOLX] Binds (in a non-immune fashion) to the Fc portion of human IgA and IgG; binding occurs on the cell surface. Confers the ability to survive exposure to human serum exposure (PubMed:10722621). Binds to the Fc portion of human IgG, IgA and to whole mouse antibodies also via Fc (PubMed:19303642). Upon overexpression cells acquire an extra cell surface layer that forms a zipper-like contact between cells; cells autoagglutinate and form biofilm more readily, suggesting it may play a role in defense against a host (PubMed:21742268).<ref>PMID:10722621</ref> <ref>PMID:19303642</ref> <ref>PMID:21742268</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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The Structure of E. coli IgG-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins.,Leo JC, Lyskowski A, Hattula K, Hartmann MD, Schwarz H, Butcher SJ, Linke D, Lupas AN, Goldman A Structure. 2011 Jul 13;19(7):1021-30. PMID:21742268<ref>PMID:21742268</ref>
The Structure of E. coli IgG-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins.,Leo JC, Lyskowski A, Hattula K, Hartmann MD, Schwarz H, Butcher SJ, Linke D, Lupas AN, Goldman A Structure. 2011 Jul 13;19(7):1021-30. PMID:21742268<ref>PMID:21742268</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2xzr" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Viruses]]
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[[Category: Enterobacteria phage P-EibD]]
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[[Category: Alvarez, B Hernandez.]]
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[[Category: Large Structures]]
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[[Category: Deiss, S.]]
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[[Category: Deiss S]]
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[[Category: Hartmann, M D.]]
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[[Category: Hartmann MD]]
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[[Category: Lupas, A N.]]
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[[Category: Hernandez Alvarez B]]
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[[Category: Ridderbusch, O.]]
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[[Category: Lupas AN]]
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[[Category: Cell adhesion]]
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[[Category: Ridderbusch O]]
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[[Category: Protein export]]
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[[Category: Taa]]
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[[Category: Trimeric autotransporter adhesin]]
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Current revision

Escherichia coli Immunoglobulin-binding protein EibD 391-438 FUSED TO GCN4 ADAPTORS

PDB ID 2xzr

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