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2xuv

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==The structure of HdeB==
==The structure of HdeB==
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<StructureSection load='2xuv' size='340' side='right' caption='[[2xuv]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='2xuv' size='340' side='right'caption='[[2xuv]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xuv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XUV OCA]. <br>
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<table><tr><td colspan='2'>[[2xuv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XUV FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xuv OCA], [https://pdbe.org/2xuv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xuv RCSB], [https://www.ebi.ac.uk/pdbsum/2xuv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xuv ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xuv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xuv RCSB], [http://www.ebi.ac.uk/pdbsum/2xuv PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/HDEB_ECOLI HDEB_ECOLI] Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.<ref>PMID:17085547</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Salt Bridges Regulate Both Dimer Formation and Monomeric Flexibility in HdeB and May Have a Role in Periplasmic Chaperone Function.,Wang W, Rasmussen T, Harding AJ, Booth NA, Booth IR, Naismith JH J Mol Biol. 2011 Nov 25. PMID:22138344<ref>PMID:22138344</ref>
Salt Bridges Regulate Both Dimer Formation and Monomeric Flexibility in HdeB and May Have a Role in Periplasmic Chaperone Function.,Wang W, Rasmussen T, Harding AJ, Booth NA, Booth IR, Naismith JH J Mol Biol. 2011 Nov 25. PMID:22138344<ref>PMID:22138344</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2xuv" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Naismith, J H.]]
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[[Category: Large Structures]]
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[[Category: Wang, W.]]
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[[Category: Naismith JH]]
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[[Category: Unknown function]]
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[[Category: Wang W]]

Current revision

The structure of HdeB

PDB ID 2xuv

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