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2y20

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==THE MECHANISMS OF HAMP-MEDIATED SIGNALING IN TRANSMEMBRANE RECEPTORS - THE A291I MUTANT==
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<StructureSection load='2y20' size='340' side='right' caption='[[2y20]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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==The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291I mutant==
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<StructureSection load='2y20' size='340' side='right'caption='[[2y20]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2y20]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y20 OCA]. <br>
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<table><tr><td colspan='2'>[[2y20]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y20 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y0q|2y0q]], [[3zrx|3zrx]], [[2y21|2y21]], [[3zrv|3zrv]], [[3zrw|3zrw]], [[2y0t|2y0t]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y20 OCA], [https://pdbe.org/2y20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y20 RCSB], [https://www.ebi.ac.uk/pdbsum/2y20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y20 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y20 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y20 RCSB], [http://www.ebi.ac.uk/pdbsum/2y20 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/O28769_ARCFU O28769_ARCFU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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The Mechanisms of HAMP-Mediated Signaling in Transmembrane Receptors.,Ferris HU, Dunin-Horkawicz S, Mondejar LG, Hulko M, Hantke K, Martin J, Schultz JE, Zeth K, Lupas AN, Coles M Structure. 2011 Mar 9;19(3):378-85. PMID:21397188<ref>PMID:21397188</ref>
The Mechanisms of HAMP-Mediated Signaling in Transmembrane Receptors.,Ferris HU, Dunin-Horkawicz S, Mondejar LG, Hulko M, Hantke K, Martin J, Schultz JE, Zeth K, Lupas AN, Coles M Structure. 2011 Mar 9;19(3):378-85. PMID:21397188<ref>PMID:21397188</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2y20" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
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[[Category: Ferris, H U.]]
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[[Category: Large Structures]]
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[[Category: Hulko, M.]]
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[[Category: Ferris HU]]
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[[Category: Lupas, A N.]]
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[[Category: Hulko M]]
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[[Category: Zeth, K.]]
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[[Category: Lupas AN]]
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[[Category: Membrane protein]]
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[[Category: Zeth K]]
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[[Category: Transmembrane signalling]]
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Current revision

The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291I mutant

PDB ID 2y20

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