3axz

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==Crystal structure of Haemophilus influenzae TrmD in complex with adenosine==
==Crystal structure of Haemophilus influenzae TrmD in complex with adenosine==
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<StructureSection load='3axz' size='340' side='right' caption='[[3axz]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='3axz' size='340' side='right'caption='[[3axz]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3axz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AXZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AXZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3axz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AXZ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ay0|3ay0]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HI_0202, trmD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3axz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3axz OCA], [https://pdbe.org/3axz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3axz RCSB], [https://www.ebi.ac.uk/pdbsum/3axz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3axz ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine-N(1)-)-methyltransferase tRNA (guanine-N(1)-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.31 2.1.1.31] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3axz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3axz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3axz RCSB], [http://www.ebi.ac.uk/pdbsum/3axz PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.,Lahoud G, Goto-Ito S, Yoshida K, Ito T, Yokoyama S, Hou YM RNA. 2011 Jul;17(7):1236-46. Epub 2011 May 20. PMID:21602303<ref>PMID:21602303</ref>
Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.,Lahoud G, Goto-Ito S, Yoshida K, Ito T, Yokoyama S, Hou YM RNA. 2011 Jul;17(7):1236-46. Epub 2011 May 20. PMID:21602303<ref>PMID:21602303</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3axz" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Haemophilus influenzae]]
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[[Category: Haemophilus influenzae Rd KW20]]
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[[Category: Goto-Ito, S.]]
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[[Category: Large Structures]]
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[[Category: Hou, Y M.]]
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[[Category: Goto-Ito S]]
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[[Category: Ito, T.]]
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[[Category: Hou YM]]
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[[Category: Yokoyama, S.]]
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[[Category: Ito T]]
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[[Category: Yoshida, K.]]
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[[Category: Yokoyama S]]
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[[Category: Adomet binding]]
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[[Category: Yoshida K]]
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[[Category: Methyltransferase]]
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[[Category: Transferase]]
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[[Category: Trefoil knot]]
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Current revision

Crystal structure of Haemophilus influenzae TrmD in complex with adenosine

PDB ID 3axz

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