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3awj

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==Crystal structure of the Huperzia serrata polyketide synthase 1 complexed with CoA-SH==
==Crystal structure of the Huperzia serrata polyketide synthase 1 complexed with CoA-SH==
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<StructureSection load='3awj' size='340' side='right' caption='[[3awj]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3awj' size='340' side='right'caption='[[3awj]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3awj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Huperzia_serrata Huperzia serrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AWJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3awj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Huperzia_serrata Huperzia serrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AWJ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3awk|3awk]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3awj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awj OCA], [https://pdbe.org/3awj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3awj RCSB], [https://www.ebi.ac.uk/pdbsum/3awj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3awj ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pks1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=355589 Huperzia serrata])</td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3awj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3awj RCSB], [http://www.ebi.ac.uk/pdbsum/3awj PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/A3E7Z7_HUPSR A3E7Z7_HUPSR]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase.,Morita H, Yamashita M, Shi SP, Wakimoto T, Kondo S, Kato R, Sugio S, Kohno T, Abe I Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13504-9. Epub 2011 Aug 8. PMID:21825160<ref>PMID:21825160</ref>
Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase.,Morita H, Yamashita M, Shi SP, Wakimoto T, Kondo S, Kato R, Sugio S, Kohno T, Abe I Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13504-9. Epub 2011 Aug 8. PMID:21825160<ref>PMID:21825160</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3awj" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Huperzia serrata]]
[[Category: Huperzia serrata]]
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[[Category: Abe, I.]]
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[[Category: Large Structures]]
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[[Category: Kato, R.]]
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[[Category: Abe I]]
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[[Category: Kohno, T.]]
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[[Category: Kato R]]
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[[Category: Kondo, S.]]
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[[Category: Kohno T]]
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[[Category: Morita, H.]]
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[[Category: Kondo S]]
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[[Category: Sugio, S.]]
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[[Category: Morita H]]
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[[Category: Chalcone synthase]]
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[[Category: Sugio S]]
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[[Category: Transferase]]
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[[Category: Type iii polyketide synthase]]
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Current revision

Crystal structure of the Huperzia serrata polyketide synthase 1 complexed with CoA-SH

PDB ID 3awj

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