3zo5
From Proteopedia
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==Structure of SENP2-Loop1 in complex with preSUMO-2== | ==Structure of SENP2-Loop1 in complex with preSUMO-2== | ||
- | <StructureSection load='3zo5' size='340' side='right' caption='[[3zo5]], [[Resolution|resolution]] 2.15Å' scene=''> | + | <StructureSection load='3zo5' size='340' side='right'caption='[[3zo5]], [[Resolution|resolution]] 2.15Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3zo5]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3zo5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZO5 FirstGlance]. <br> |
- | </td></tr><tr><td class="sblockLbl"><b> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zo5 OCA], [https://pdbe.org/3zo5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zo5 RCSB], [https://www.ebi.ac.uk/pdbsum/3zo5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zo5 ProSAT]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/SENP2_HUMAN SENP2_HUMAN] Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway (By similarity).<ref>PMID:12192048</ref> <ref>PMID:11896061</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structural insights into the SENP6 Loop1 structure in complex with SUMO2.,Alegre KO, Reverter D Protein Sci. 2014 Apr;23(4):433-41. doi: 10.1002/pro.2425. Epub 2014 Mar 10. PMID:24424631<ref>PMID:24424631</ref> | Structural insights into the SENP6 Loop1 structure in complex with SUMO2.,Alegre KO, Reverter D Protein Sci. 2014 Apr;23(4):433-41. doi: 10.1002/pro.2425. Epub 2014 Mar 10. PMID:24424631<ref>PMID:24424631</ref> | ||
- | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
+ | <div class="pdbe-citations 3zo5" style="background-color:#fffaf0;"></div> | ||
+ | |||
+ | ==See Also== | ||
+ | *[[SUMO 3D Structures|SUMO 3D Structures]] | ||
+ | *[[Sentrin-specific protease|Sentrin-specific protease]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Alegre | + | [[Category: Alegre KO]] |
- | [[Category: Reverter | + | [[Category: Reverter D]] |
- | + |
Current revision
Structure of SENP2-Loop1 in complex with preSUMO-2
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