4lxs

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:27, 20 September 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)==
==Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)==
-
<StructureSection load='4lxs' size='340' side='right' caption='[[4lxs]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
+
<StructureSection load='4lxs' size='340' side='right'caption='[[4lxs]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4lxs]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LXS FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4lxs]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LXS FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene><br>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e07|3e07]], [[4lxr|4lxr]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tl, CG5490 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME]), spz, CG6134 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lxs OCA], [https://pdbe.org/4lxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lxs RCSB], [https://www.ebi.ac.uk/pdbsum/4lxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lxs ProSAT]</span></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lxs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lxs RCSB], [http://www.ebi.ac.uk/pdbsum/4lxs PDBsum]</span></td></tr>
+
</table>
-
<table>
+
== Function ==
 +
[https://www.uniprot.org/uniprot/TOLL_DROME TOLL_DROME]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 14: Line 16:
Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.,Parthier C, Stelter M, Ursel C, Fandrich U, Lilie H, Breithaupt C, Stubbs MT Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6281-6. doi:, 10.1073/pnas.1320678111. Epub 2014 Apr 14. PMID:24733933<ref>PMID:24733933</ref>
Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.,Parthier C, Stelter M, Ursel C, Fandrich U, Lilie H, Breithaupt C, Stubbs MT Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6281-6. doi:, 10.1073/pnas.1320678111. Epub 2014 Apr 14. PMID:24733933<ref>PMID:24733933</ref>
-
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4lxs" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Drome]]
+
[[Category: Drosophila melanogaster]]
-
[[Category: Breithaupt, C.]]
+
[[Category: Large Structures]]
-
[[Category: Parthier, C.]]
+
[[Category: Breithaupt C]]
-
[[Category: Stelter, M.]]
+
[[Category: Parthier C]]
-
[[Category: Stubbs, M T.]]
+
[[Category: Stelter M]]
-
[[Category: Cytokine receptor]]
+
[[Category: Stubbs MT]]
-
[[Category: Embryonic development]]
+
-
[[Category: Immune system]]
+
-
[[Category: Immune system-cytokine complex]]
+
-
[[Category: Innate immunity]]
+
-
[[Category: Leucine-rich repeat]]
+
-
[[Category: Receptor-ligand complex]]
+
-
[[Category: Tlr]]
+

Current revision

Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)

PDB ID 4lxs

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4lxs"
Personal tools